HIV drug resistance (HIVDR) can decrease the effectiveness of antiretroviral drugs, and this study focused on assessing HIV-1 subtypes and drug resistance among key populations in Vietnam during 2018 and 2020.
The study recruited participants from hotspots for men who have sex with men (MSM) and female sex workers (FSW) in various provinces, and 42.5% of HIV-positive samples had a viral load indicating the need for further testing for drug resistance.
The results showed that CRF01_AE was the most common subtype, and 16.7% of participants had drug resistance mutations, with the majority being associated with NNRTI and NRTI classes, suggesting