A new 14-membered cembrane-type diterpenoid and other constituents from the aerial parts of Jacq. and their antibacterial activity.

A new 14-membered cembrane- diterpenoid, jatrophainolide D (), along with six known compounds, ()-phytol (), lupeol (), stigmasterol (), ergosta-4,6,8 (14),22-tetraen-3-one (), stigmast-4-ene-3-one (), and ergosterol peroxide () were isolated from the aerial parts of . The structure of isolates was elucidated by IR, UV, 1D-/2D-NMR, and HRESI-TOFMS data as well as by comparison with the reported spectroscopic data. All isolates were evaluated the antibacterial activity against , , , , , and .

High prevalence of soil-transmitted helminths among primary students in Ha Giang, Vietnam: A descriptive cross-sectional study.

Despite improvements in environmental sanitation and healthcare, the infection rate of soil-transmitted helminths (STHs) remains high in low socioeconomic regions of developing countries including Vietnam. This study aimed to determine the prevalence and intensity of STH infections among primary school children in Meo Vac, Ha Giang: a poor mountainous province in Vietnam. A descriptive cross-sectional study was conducted from October to November 2023, involving 400 participants.

Photocatalytic degradation performance of a chitosan/ZnO-FeO nanocomposite over cationic and anionic dyes under visible-light irradiation.

The sonochemical synthesis of a chitosan-ZnO/FeO nanocomposite yielded a highly porous structure and large surface area for enhancing the photocatalytic degradation of cationic (rhodamine B, RhB) and anionic (methyl orange, MO) dyes in aqueous solution. Chitosan-ZnO/FeO demonstrated a significant enhancement in photodegradation efficiency 99.49% for MO ( = 5.

Unmasking Long QT Syndrome in a Serviceman: Effects of Hypoglycemia and a Flight Duty Medical Examination.

We report the case of a 29-year-old male soldier with a time in service above 10 years, found to have asymptomatic long QT syndrome (LQTS), a condition associated with increased risk of potentially fatal ventricular arrhythmias, during a flight physical. A review of his past medical history revealed a transient QT prolongation during an episode of hypoglycemia due to endogenous hyperinsulinism caused by an insulinoma, as an infantryman 7 years earlier; the resolution of the QT prolongation was spontaneous. He was evaluated and considered fit for duty by cardiology.

AI-Based Discrimination of Faradaic Current against Nonfaradaic Current Inspired by Speech Denoising.

Cyclic voltammetry (CV) has been a powerful technique to provide impactful insights for electrochemical systems, including reaction mechanism, kinetics, diffusion coefficients, etc., in various fields of study, notably energy storage and energy conversion. However, the separation between the faradaic current component of CV and the nonfaradaic current contribution to extract useful information remains a major issue for researchers.

Accuracy of Capillary Blood for Assessing Vitamin A Nutritional Status Among Children Under 7 Years of Age: A Multicenter Study.

Vitamin A deficiency remains a major public health problem worldwide, particularly among young children. Capillary blood has the potential for application in vitamin A assessment. The aim of this study is to validate the accuracy of capillary blood for assessing vitamin A nutritional status among young children.

Clinico-pathological factors and [F]FDG PET/CT metabolic parameters for prediction of progression-free survival in radioiodine refractory differentiated thyroid carcinoma.

Objective: Identifying prognostic markers for clinical outcomes is crucial in selecting appropriate treatment options for patients with radioiodine-refractory (RAI-R) differentiated thyroid carcinoma (DTC). The aim of this study was to investigate the prognostic value of clinico-pathological features and semiquantitative [F]FDG PET/CT metabolic parameters in predicting progression-free survival (PFS) in DTC patients with RAI-R.

Patients And Methods: This prospective cohort study included 110 consecutive RAI-R DTC patients who were referred for [F]FDG PET/CT imaging.

Sleep deprivation alters hepatic UGT1A9 and propofol metabolism in mice.

Sleep deprivation (SD) causes circadian misalignment, and circadian clock disruption is associated with metabolic diseases such as obesity, insulin resistance, and diabetes. However, the underlying mechanism for SD-induced circadian clock disruption as well as metabolic enzyme changes is still lacking. Here, we developed SD sensitizes mice with disrupted circadian rhythms to demonstrate the regulation role and mechanism of SD in UDP-glucuronosyltransferases (UGTs) expression and the metabolism of corresponding substrates.

The Function of Green Finance Initiative in Maintaining Ocean Health: Novel Findings From an International Database.

This article empirically analyzes the influence of green finance (GF) on ocean health. Employing 10 indicators and a composite Ocean Health Index (OHI) to measure the efficiency and sustainability of ocean economies, the study spans 9 years across 35 countries. Multiple econometric methodologies, including Feasible Generalized Least Squares (FGLS), Panel-Corrected Standard Errors (PCSE), and the 2-step Generalized Method of Moments (GMM), demonstrate a substantial negative association between GF and ocean health.

The impact of qualitative [18F]FDG PET/CT in predicting clinical outcomes of post-surgical differentiated thyroid cancer patients with elevated thyroglobulin and negative radioiodine whole-body scan.

Background: [F]FDG PET/CT has been widely used as a diagnostic tool in detection and localization of recurrent non-avid radioiodine lesions in post-operative differentiated thyroid cancer (DTC) patients with elevated serum thyroglobulin but negative radioiodine whole-body scan (TENIS) syndrome. The aim of our study was to evaluate the role of [F]FDG PET/CT in prediction on outcomes of these DTC patients.

Methods: Post-operative DTC patients with TENIS syndrome were collected in the department of nuclear medicine, Hospital 108 from 2019 to 2023.

Application of stable isotopes and mineral elements fingerprinting for beef traceability and authenticity in inner mongolia of China.

In recent years, the origin and safety of counterfeit meat products have raised significant concerns among consumers. Therefore, there was an urgent need to develop a new method using fingerprinting techniques for meat product traceability. This study aimed to evaluate the traceability and authenticity of beef from Inner Mongolia by measuring the δC and δN values, as well as 13 mineral elements.

Disruption Dynamics and Charge Transfer of a Single Attoliter Emulsion Droplet Revealed by Combined Fast-Scan Sinusoidal Voltammetry and Short Time Fourier Transform Analysis.

Single-entity electrochemistry has gained significant attention for the analysis of individual cells, nanoparticles, and droplets, which is leveraged by robust electrochemical techniques such as chronoamperometry and cyclic voltammetry (CV) to extract information about single entities, including size, kinetics, mass transport, etc. For an in-depth understanding such as dynamic interaction between the electrode and a single entity, the unconventional fast electrochemical technique is essential for time-resolved analysis. This fast experimental technique is unfortunately hindered by a substantial nonfaradaic response.

BNST CRF receptor type 1 modulates mechanical hypersensitivity induced by adolescent alcohol exposure in adult female mice.

Rationale: Alcohol exposure during adolescence has been linked to long-lasting behavioral consequences, contributing to the development of alcohol use disorder. Negative affect and chronic pain during alcohol withdrawal are critical factors influencing problematic alcohol use and relapse. Our previous research demonstrated that adolescent intermittent ethanol (AIE) vapor exposure elicits sex-specific negative affect-like behavior in adult mice following stress exposure.

Effect of Tissue-derived Angiotensinogen on Kidney Injury and Fibrosis in Obstructive Nephropathy.

Background/aim: Angiotensinogen (AGT), a precursor of angiotensin II (AngII), contributes to regulating (patho)physiological conditions, including blood pressure changes, inflammation, and kidney fibrosis. However, the precise role of tissue-specific AGT in kidney fibrosis independent of blood pressure remains to be fully understood. This study investigated the source of intrarenal AGT and its role in kidney injury and fibrosis during obstructive nephropathy.

Activity restriction and risk of adverse pregnancy outcomes.

Background: Activity restriction is a common recommendation given to patients during pregnancy for various indications, despite lack of definitive data showing improvements in pregnancy outcomes.

Objective: To determine if activity restriction (AR) in pregnancy is associated with decreased odds of adverse pregnancy outcomes (APOs).

Study Design: Secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b) prospective cohort.

Does circularity mean environmental sustainability? Novel evidence from European countries.

The objective of this research is to evaluate the effects of green economy initiatives (GEI) on environmental sustainability (ES) through empirical means. The degree of green economy efforts is measured using six different metrics: the percentage of circular material consumption (GEI_MA), municipal trash generation per person (GEI_MW), recycling waste performance (GEI_RW), and recycling and secondary raw materials-related patents (GEI_PA). The latter particularly comprises the biowaste (GEI_RB) and e-waste (GEI_RE) recycling shares.

Global research states and trends of micro RNA in irritable bowel syndrome: a bibliometric analysis.

Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, but its diagnosis and treatment remain obscure. Non-coding RNAs (ncRNAs), as potential biomarkers, have attracted increasing attention in digestive diseases. Here, we present a comprehensive research status, development trends, and valuable insights in this subject area.

Employment of the DCC-GARCH Copula Model to explore a link between robotics and artificial intelligence and green crypto investments.

The pursuit of the Sustainable Development Goals (SDGs) requires considerable new green crypto investments. To attract the flow of this investment, it is necessary to develop and apply robotic artificial intelligence (AI) as it has the potential to encourage the adoption of environmental innovation and increase individuals' environmental awareness. Our research employs the DCC-GARCH Copula Model to examine time-varying spillovers and prove interlinkages between the development of AI and green cryptocurrencies in the period from January 1, 2018, to September 8, 2023.