Waste to protein: A systematic review of a century of advancement in microbial fermentation of agro-industrial byproducts.

Increasing global consumption of protein over the last five decades, coupled with concerns about the impact on emissions of animal-based protein production, has created interest in alternative protein sources. Microbial proteins (MPs), derived through the fermentation of agro-industrial byproducts, present a promising option. This review assesses a century of advancements in this domain.

Environmental stewardship: A systematic scoping review.

Environmental stewardship is a term describing both the philosophy and the actions required to protect, restore, and sustainably use natural resources for the future benefit of the environment and society. In this paper, we review the environmental science literature to map the types of practical actions that are identified as 'environmental stewardship' using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for scoping reviews. We specifically mapped: 1) the type of actions and outcomes targeting the natural environment that have been categorized as environmental stewardship, 2) the main actors, and the underlying factors influencing their environmental stewardship actions, and 3) the methods used to mobilize environmental stewardship actions once these factors are known.

Anticipatory regulation for pandemic responses: are we there yet?

Can drug and vaccine regulatory agencies leverage their experience during the coronavirus disease 2019 (COVID-19) pandemic to advance from reactive regulation to adaptive regulation and beyond to anticipatory regulation to prevent or curb future pandemics?

Purchasing sustainable palm oil products: narrowing the intention-behavior gap.

Experts on palm oil production and utilization emphasize the role of consumer purchasing power in dealing with the environmental and social impacts of the palm oil crisis -that by increasing the demand for sustainable palm oil (SPO), greater supply will follow. However, research has identified a persistent intention-behavior gap. Even knowledgeable consumers do not always follow through on their intentions to purchase SPO.

Audience segmentation of New Zealand cat owners: Understanding the barriers and drivers of cat containment behavior.

Free-roaming companion cats have a detrimental impact on the environment and are at risk of harm. Despite these negative impacts, it is the norm in New Zealand (NZ) to allow companion cats to roam freely and only a minority of cat owners practice cat containment. This study firstly sought to identify what factors act as barriers and drivers of NZ owners' participation in cat containment, and secondly whether NZ owners could be segmented into unique audiences based on the factors predicting their cat containment behavior.

Protecting and restoring freshwater biodiversity across urban areas in Aotearoa New Zealand: Citizens' reporting of pollution in stormwater drains and waterways.

Urbanization poses numerous challenges to freshwater biodiversity. This paper describes two studies with the joint aim of demonstrating the benefits of applying a systematic behaviour change framework and providing the foundational knowledge to inform future behavior change work to protect and restore urban freshwater biodiversity. In Study 1 we used a mixed-methods research design, involving 14 key informant interviews followed by an online survey targeting 17 freshwater biodiversity experts and another targeting a representative sample of 550 urban residents, to identify and prioritize the most promising resident behaviors to target to reduce stormwater pollution and improve natural waterway habitats in urban areas.

Airborne gamma-ray mapping using fixed-wing vertical take-off and landing (VTOL) uncrewed aerial vehicles.

Low-cost uncrewed aerial vehicles (UAVs) are replacing manned aircraft for airborne radiation mapping applications such as nuclear accident response scenarios or surveying ore deposits and mine sites because of their cost-effectiveness and ability to conduct surveys at lower altitude compared to manned counterparts. Both multi-rotor UAVs and fixed-wing UAVs are well established technologies for aerial radiation mapping applications, however, both also have drawbacks: multi-rotor UAVs are very limited in flight time and range, and fixed-wing UAVs usually require facilities for take-off and landing. A compromise solution is introduced in this work, using a fixed-wing vertical take-off and landing (VTOL) UAV that combines the flexibility of a multi-rotor UAV with the range and flight time of a fixed-wing UAV.

Australian Youth Mental Health and Climate Change Concern After the Black Summer Bushfires.

Climate change and its effects present notable challenges for mental health, particularly for vulnerable populations, including young people. Immediately following the unprecedented Black Summer bushfire season of 2019/2020, 746 Australians (aged 16-25 years) completed measures of mental health and perceptions of climate change. Results indicated greater presentations of depression, anxiety, stress, adjustment disorder symptoms, substance abuse, and climate change distress and concern, as well as lower psychological resilience and perceived distance to climate change, in participants with direct exposure to these bushfires.

Delivering impactful solutions for the bioeconomy.

We are increasingly challenged to operate within our planetary boundaries, while delivering on United Nations (UN) Sustainable Development Goal (SDG) 2030 targets, and net-zero emissions by 2050. Failure to solve these challenges risks economic, social, political, climate, food, water, and fuel security. Therefore, new, scalable, and adoptable circular economy solutions are urgently required.

Palm oil: Understanding barriers to sustainable consumption.

Palm oil is relatively inexpensive, versatile, and popular, generating great economic value for Southeast Asian countries. However, the growing demand for palm oil is leading to deforestation and biodiversity loss. The current study is the first to employ a capability-opportunity-motivation (COM-B) framework in green consumerism, to determine which capability, opportunity, and motivation factors strongly predict the intentional purchasing of sustainable palm oil products by Australian consumers (N = 781).

How personal values shape job seeker preference: A policy capturing study.

Does the "ideal" organization exist? Or do different workplace attributes attract different people? And if so, what attributes attract what types of employees? This study combines person-organization fit theory and a policy capturing methodology to determine (a) which attributes are the strongest predictors of perceived organization attractiveness in a sample of Australian job seekers, and (b) whether the magnitude of these predictive effects varies as a function of job seekers' personal values. The design of this study is a randomized experiment of Australian job seekers who responded to an online survey invitation. Each of the 400 respondents received a random subset of 8 of 64 possible descriptions of organizations.

Assessing the Impact of US Food and Drug Administration Breakthrough Therapy Designation Timing on Trial Characteristics and Development Speed.

The US Congress created the Breakthrough Therapy designation in 2012 to expedite drug development and review through efficient clinical trial design and intensive interaction with US Food and Drug Administration (FDA) reviewers. Yet, of the 116 pivotal trials supporting Breakthrough-designated drugs approved 2013-2018, 96 (83%) were already underway or completed when the designation was granted, limiting the potential of the designation to influence trial design. We found no difference between these trials and the 20 (17%) that had not yet begun when the designation was granted (which had greater potential to be impacted by the designation) with respect to phase, size, intervention model (single-arm vs.

Immune-Mobilizing Monoclonal T Cell Receptors Mediate Specific and Rapid Elimination of Hepatitis B-Infected Cells.

Background And Aims: Therapies for chronic hepatitis B virus (HBV) infection are urgently needed because of viral integration, persistence of viral antigen expression, inadequate HBV-specific immune responses, and treatment regimens that require lifelong adherence to suppress the virus. Immune mobilizing monoclonal T Cell receptors against virus (ImmTAV) molecules represent a therapeutic strategy combining an affinity-enhanced T Cell receptor with an anti-CD3 T Cell-activating moiety. This bispecific fusion protein redirects T cells to specifically lyse infected cells expressing the target virus-derived peptides presented by human leukocyte antigen (HLA).

Working Hard or Hardly Working? Regulatory Bottlenecks in Developing a COVID-19 Vaccine.

Vaccine solutions rarely reach the public until after an outbreak abates; an Ebola vaccine was approved 5 years after peak outbreak and SARS, MERS, and Zika vaccines are still in clinical development. Despite massive leaps forward in rapid science, other regulatory bottlenecks are hamstringing the global effort for pandemic vaccines.

Self-compassion, physical health, and health behaviour: a meta-analysis.

This meta-analysis investigated relationships between self-compassion and (1) physical health and (2) health-promoting behaviour in a large pooled sample ( = 29,588) sourced from 94 peer-reviewed articles. As hypothesised, omnibus analyses revealed positive associations between self-compassion and both physical health (= .18) and health behaviour (= .

Does Green-Person-Organization Fit Predict Intrinsic Need Satisfaction and Workplace Engagement?

The current study assessed whether high green-person-organization fit (GPO; the extent to which an organization's commitment to pro-environmental outcomes is congruent with its employees' environmental values) predicts employees' intrinsic need satisfaction and engagement in the workplace. The sample consisted of 818 full-time Australian workers, which is sourced from an online panel. Consistent with the GPO model, pro-environmental work climate was a more potent predictor of intrinsic need satisfaction and engagement for employees with strong ecocentric values than those with weak ecocentric values.

Can work climate foster pro-environmental behavior inside and outside of the workplace?

Guided by self-determination theory, we investigated the potential impact of work climate on employee motivation, and pro-environmental behavior (PEB) inside and outside of the workplace. We found that in workplaces with stronger pro-environmental climates and at least moderate levels of autonomy support, employees reported higher levels of autonomous motivation to engage in PEB. In turn, autonomously motivated employees engaged in more PEBs, both inside and outside the workplace.

Change the Humans First: Principles for Improving the Management of Free-Roaming Cats.

In Australia, free-roaming cats can be found in urban and rural areas across the country. They are inherently difficult to manage but it is frequently human behaviour that demands the most attention and is in most need of change. To the frustration of policy makers and practitioners, scientific knowledge, technological developments, and legal and institutional innovations, often run afoul of insufficient public capacity, opportunity and motivation to act.

Using Audience Segmentation to Understand Nonparticipation in Invasive Mammal Management in Australia.

Invasive mammals threaten agriculture, biodiversity, and community health. Yet many landholders fail to engage in control activities recommended by experts. We surveyed a representative sample of 731 Western Australian rural landholders.

Feelings About Fracking: Using the Affect Heuristic to Understand Opposition to Coal Seam Gas Production.

The rapid expansion of coal seam gas (CSG) extraction across Australia has polarized public opinion about the risks, benefits, and the future of the industry. We conducted a randomized controlled experiment to assess the impact of CSG messaging on opposition to the CSG industry. Residents of a major Australian city (N = 549), aged between 21 and 87 years, were randomly assigned to view one of three brief video messages (pro-CSG, anti-CSG, or a neutral control) sourced from the Internet.

Increasing belief but issue fatigue: Changes in Australian Household Climate Change Segments between 2011 and 2016.

Using national Australian samples collected in 2011 (n = 1927) and 2016 (n = 2503), we identified six Australian household segments which we labelled Alarmed, Concerned, Cautious, Disengaged, Doubtful and Dismissive. Between the two periods, we found the proportion of households in the Alarmed and Concerned segments was stable; however there was a decrease (28% to 20%) in the proportion of households in the Doubtful and Dismissive segments and an increase (27% to 33%) in the Cautious and Disengaged segments. We found that a greater proportion of households have personally experienced climate change, and were more likely to believe in human causation and believe that there is a scientific consensus about the issue.

Long-term electrical performance of Attain Performa quadripolar left ventricular leads with all steroid-eluting electrodes: Results from a large worldwide clinical trial.

Background: Steroid-eluting (SE) electrodes suppress local inflammation and lower pacing capture thresholds (PCT); however, their effectiveness on quadripolar left ventricular (LV) leads in the cardiac vein is not fully studied. We evaluated the effectiveness of SE on all four LV pacing electrodes in human subjects enrolled in the Medtronic Attain® Performa™ quadripolar LV lead study.

Methods: A total of 1,097 subjects were included in this evaluation.

Precision Medicines Have Faster Approvals Based On Fewer And Smaller Trials Than Other Medicines.

Precision medicines can benefit patients by increasing the probability of a successful treatment response in selected patient populations. The potential for more immediate signals of efficacy during clinical trials suggests such medicines will reach the market more rapidly than traditional drugs will. Using data from the Food and Drug Administration (FDA), we examined the regulatory review and pivotal trial characteristics of precision medicines.