Publications by authors named "H-J Kurth"

Background: Non-melanoma skin cancers (NMSCs) are responsible for up to one-third of all human malignancies. Surgery is usually the treatment of choice, but patients often experience pain during the procedure. Topical rhenium-188 resin skin cancer treatment (RSCT) may be a valid therapeutic alternative.

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Introduction: Despite growing awareness of post-coronavirus disease 2019 (COVID-19) cholangiopathy as one of the most serious long-term gastrointestinal consequences of COVID-19, the endoscopic features of this disease are still poorly characterized. This study aimed to more precisely define its endoscopic features and to outline the role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of this entity.

Methods: In this observational study, 46 patients with confirmed post-COVID-19 cholangiopathy were included.

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COVID-19 has highly variable clinical courses. The search for prognostic host factors for COVID-19 outcome is a priority. We performed logistic regression for ICU admission against a polygenic score (PGS) for Cystatin C (CyC) production in patients with COVID-19.

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Article Synopsis
  • Longitudinal studies of the innate immune system are crucial for understanding how COVID-19 progresses and affects the body.
  • In a study involving 205 patients, researchers characterized natural killer (NK) cells and found that severe COVID-19 is linked with high levels of interferon (IFN)-α and decreased NK cell function.
  • The findings suggest that distinct immune responses (IFN-α in severe cases and tumor necrosis factor in moderate cases) contribute to varying disease severities and that ongoing NK cell dysfunction may lead to complications like fibrotic lung disease.
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Objective: To examine the effect of sex on clinical response to triptans in migraine and to determine whether these differences are related to pharmacokinetics of triptans in men and women, we performed a systematic review and meta-analysis.

Methods: We searched clinical trials distinguishing clinical response to or pharmacokinetic parameters of triptans between sexes in PubMed, MEDLINE, Cochrane Library, Embase, and Web of Science up to Dec 12, 2019. Analysis was based on data extracted from published reports.

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Geriatric medicine is a rapidly evolving field that addresses diagnostic, therapeutic and care aspects of older adults. Some disabilities and disorders affecting cognition (e.g.

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