Publications by authors named "H el Sayegh"

Introduction: Multilocular cystic nephroma is an uncommon condition with only few cases described in the literature, although its benign nature is well-recognized.

Case Presentation: We present a case of a 28-year-old male patient who presented with a right flank pain, imaging suspected a multicystic renal cell carcinoma. A radical nephrectomy was performed view the size of the cyst and the high tumor complexity, which histology confirmed the diagnosis of multilocular cystic nephroma.

View Article and Find Full Text PDF

Purpose: Novel therapies targeting specific genomic alterations are a promising treatment approach for relapsed/refractory cancer. Patients with specific alterations may be more likely to respond. Trial designs should maximize opportunities for such patients to enroll on these trials.

View Article and Find Full Text PDF

Introduction: Urethral caruncle is a benign lesion located at the urethral meatus, predominantly affecting postmenopausal women. Though often asymptomatic, it can sometimes present with symptoms that significantly impact the patient's quality of life. Diagnosis is usually straightforward based on physical examination.

View Article and Find Full Text PDF
Article Synopsis
  • - Hypertension (HTN) is the most common additional health issue found in cancer patients, affecting both those with pre-existing conditions and those who develop it due to cancer treatments.
  • - Various cancer therapies, such as VEGF inhibitors, Bruton tyrosine kinase inhibitors, and proteasome inhibitors, have been linked to the onset of HTN in patients.
  • - The causes of hypertension from these therapies can be due to direct effects on blood vessels (like with VEGF inhibition) or other unclear mechanisms not fully understood yet.
View Article and Find Full Text PDF

In recent years, the utilization of enterocystoplasty for bladder function enhancement has increased, albeit accompanied by risks such as stone formation, necessitating vigilant follow-up. We report a case of a 60-year-old female with a neobladder who presented with back pain, constipation, and pelvic heaviness, revealing multiple large stones in imaging. Stone analysis showed calcium oxalate and magnesium.

View Article and Find Full Text PDF