Publications by authors named "H de Lencastre"

Article Synopsis
  • Enterococci, which are typically harmless bacteria in the gut, have become opportunistic pathogens known for their antibiotic resistance and are significant causes of hospital infections globally.
  • In a study, researchers screened 295 samples from livestock and various environments for Enterococci, discovering that 90.5% were positive, with notably high rates in livestock compared to environmental samples, though none showed vancomycin resistance.
  • The analysis revealed a variety of antibiotic resistance among isolates and identified several virulence factors, with some non-clinical strains displaying characteristics that are often found in clinical isolates, despite no direct link being established between them and hospital infections.
View Article and Find Full Text PDF

Streptococcus pneumoniae carriage studies are crucial to monitor changes induced by use of pneumococcal conjugate vaccines and inform vaccination policies. In this cross-sectional study, we examined changes within the pneumococcal population following introduction of PCV13 in 2015 in the National Immunization Program (NIP), in Portugal. In 2018-2020 (NIP-PCV13), we obtained 1450 nasopharyngeal samples from children ≤6 years attending day-care.

View Article and Find Full Text PDF

Carbapenem-resistant Klebsiella pneumoniae (CR-KP) are a public health concern, causing infections with a high mortality rate, limited therapeutic options and challenging infection control strategies. In Portugal, the CR-KP rate has increased sharply, but the factors associated with this increase are poorly explored. In order to address this question, phylogenetic and resistome analysis were used to compare the draft genomes of 200 CR-KP isolates collected in 2017-2019 from five hospitals in the Lisbon region, Portugal.

View Article and Find Full Text PDF

The non-human primate (NHP) Leontopithecus rosalia is an endangered species native of Brazil and lives in forest fragments with different levels of contact with humans (natural, private and urban). Other NHPs - Callithrix spp. - were introduced by humans and co-exist and interact with the native species in these forests.

View Article and Find Full Text PDF

(1) Background: With increasing international travel and mass population displacement due to war, famine, climate change, and immigration, pathogens, such as (), can also spread across borders. Methicillin-resistant (MRSA) most commonly causes skin and soft tissue infections (SSTIs), as well as more invasive infections. One clonal strain, USA300, originating in the United States, has spread worldwide.

View Article and Find Full Text PDF