Radiation-induced nephrotoxicity: Role of SMPDL3b.

Background: Radiation nephropathy (RN) can be a significant late complication after radiotherapy for abdominal and paraspinal tumors. The mechanisms for the development of RN are thought to involve disruption of podocyte function, leading to podocyte cell death and, finally, impaired renal function. This study investigated the mechanistic role of SMPDL3b in regulating podocyte injury and renal function after irradiation.

Analysis of depressions indicative of dural venous sinuses within the intracranial cavities of skull bases.

Purpose: This study aimed to examine the anatomical variations and morphometric characteristics of the sulci in the dural venous sinuses within the intracranial cavity, with a particular focus on sex differences and asymmetry.

Methods: Thirty fixed cadaveric heads were used to measure the dimensions (length, width, and depth) and spatial relationships of the dural venous sinus sulci within the intracranial cavity, including the distance to the midline, distance to each other, and lateral margin of the skull. Comparisons were made between sexes and sides of the body.

Altered body balance and plantar pressure distribution in young adults with forward head posture.

Background: Forward head posture (FHP), a common postural issue, affects balance and may be linked to altered muscle activity and cervical spine alignment. This study investigated the impact of FHP on static balance and plantar pressure distribution in adults. We hypothesized that FHP would be associated with poorer balance and altered pressure distribution.