Publications by authors named "H Yuceyar"
Article Synopsis
- Intestinal metaplasia (IM) and Helicobacter pylori (HP) are identified as risk factors for developing gastric cancer (GC), with the WNT signaling pathway playing a significant role in this transition.
- A study involving 104 patients analyzed the expression of WNT pathway-related genes in those with GC, IM, and control groups using advanced PCR methods.
- Results showed that the genes RHOA, CSNK1A1, DVL2, FZD8, and LRP5 were overexpressed in GC and IM patients, particularly in those with metastasis or HP positivity, indicating these genes might serve as poor prognosis biomarkers for gastric cancer.
Background/Aims This study aimed to determine the prevalence of cytomegalovirus (CMV) infection among patients with moderate to severe active ulcerative colitis (UC) and to determine the risk factors for CMV infection according to the demographic features of these patients. Patients/Methods A total of 183 patients with severe or moderate active UC were enrolled in the study after retrospective analysis. The disease severity of UC was determined according to the Mayo Score.
View Article and Find Full Text PDFObjective: At present, there is no reliable indicator for dietary compliance and disease severity in patients with celiac disease (CD). The aim of this study is to evaluate mean platelet volume (MPV) level as a biomarker for detection of disease activation, dietary adherence, and assessment of disease severity.
Methods: Eighty-one patients with CD and 50 healthy subjects were enrolled in this study.
Gastric cancer (GC) development can be attributed to several risk factors including atrophic gastritis (AG), intestinal metaplasia (IM), and the presence of Helicobacter pylori (HP). Also, histone modification is an epigenetic mechanism that plays a pivotal role in GC carcinogenesis. In this preliminary study, we aimed to describe the expression profiles of histone modification in the AG, IM, and GC patient groups.
View Article and Find Full Text PDFBackground/aims: Atrophic gastritis (AG), intestinal metaplasia (IM), and Helicobacter pylori (HP) are the risk factors for the development of gastric cancer (GC). Chromatin remodeling is one of the epigenetic mechanisms involved in the carcinogenesis of GC. The purpose of this study was to investigate the expression profiles of defined chromatin remodeling genes in gastric mucosal samples and their values as gastric carcinogenesis biomarkers.
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