Behavior modeling for a new flexure-based mechanism by Hunger Game Search and physics-guided artificial neural network.

Compliant mechanism has some advantages and has been widely applied in many accurate positioning systems. However, modeling the compliant mechanism behavior has suffered from many challenges, such as unstable results, and the limitation of training data set. In the field of compliant mechanism modeling, there has been no research interested in applying meta-heuristics optimization algorithms to optimize the weights and biases of the neural network globally.

Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study.

Background: Vietnam experienced the first COVID-19 domestic outbreak due to the Wuhan strain (B.1.1) in Da Nang from July 2020.

Gut bacterial sphingolipid production modulates dysregulated skin lipid homeostasis.

Sphingolipids are an essential lipid component of the skin barrier with alterations in skin sphingolipid composition associated with multiple skin disorders including psoriasis, atopic dermatitis, and ichthyosis. Contributions to skin sphingolipid abundance are not well characterized, thus the main method of modulating skin lipid levels is the topical application of creams rich with sphingolipids at the skin surface. Evidence that diet and gut microbiome function can alter skin biology proposes an intriguing potential for the modulation of skin lipid homeostasis through gut microbial metabolism, but potential mechanisms of action are not well understood.

Evaluating Proton Versus Photon Therapy: A Call for Nuanced Decision-Making.

This letter critically evaluates the conclusions drawn by Li et al. (https://doi.org/10.

Impact of Locum Tenens Providers on Delivery of Pediatric Surgical Care.

Introduction: We sought to understand the impact of locum tenens surgeons on pediatric surgical care delivery.

Methods: We conducted a cross-sectional survey of Children's Hospital Association pediatric surgical practices. Anonymous electronic surveys were used to investigate locum tenens utilization, primary reason for use, limitations on clinical activities, and variations in practice standards or quality.