Characterization of Factors Associated With Death in Deceased Patients With Mitochondrial Disorders: A Multicenter Cross-Sectional Survey.

Background And Objectives: Mitochondrial disorders are multiorgan disorders resulting in significant morbidity and mortality. We aimed to characterize death-associated factors in an international cohort of deceased individuals with mitochondrial disorders.

Methods: This cross-sectional multicenter observational study used data provided by 26 mitochondrial disease centers from 8 countries from January 2022 to March 2023.

Amelioration of premature aging in Werner syndrome stem cells by targeting SHIP/AKT pathway.

Background: Pathogenic or null mutations in WRN helicase is a cause of premature aging disease Werner syndrome (WS). WRN is known to protect somatic cells including adult stem cells from premature senescence. Loss of WRN in mesenchymal stem cells (MSCs) not only drives the cells to premature senescence but also significantly impairs the function of the stem cells in tissue repair or regeneration.

Breast Cancer Survivors' Diet and Physical Activity Preferences and Barriers: How COVID-19 Changed the Intervention Landscape.

Background: Existing studies on breast cancer survivors (BCS) have primarily focused on individual aspects of either diet or exercise preferences and barriers. Our study aims to examine BCS' perceptions toward diet and exercise combined. Given the transformative impact of COVID-19, there is a crucial need for insights in the post-pandemic era to address the distinct challenges faced by BCS in maintaining their health and well-being.

Cyberbullying Victimization and Mental Health Symptoms Among Children and Adolescents: A Meta-Analysis of Longitudinal Studies.

Cyberbullying victimization and mental health symptoms are major concerns for children and adolescents worldwide. Despite the increasing number of longitudinal studies of cyberbullying and mental health among this demographic, the robustness of the causal associations between cyberbullying victimization and the magnitude of mental health symptoms remains unclear. This meta-analysis investigated the longitudinal impact of cyberbullying victimization on mental health symptoms among children and adolescents.

Monitoring of indoor air quality at a large sailing cruise ship to assess ventilation performance and disease transmission risk.

Large passenger ships are characterised as enclosed and crowded indoor spaces with frequent interactions between travellers, providing conditions that facilitate disease transmission. This study aims to provide an indoor ship CO dataset for inferring thermal comfort, ventilation and infectious disease transmission risk evaluation. Indoor air quality (IAQ) monitoring was conducted in nine environments (three cabins, buffet, gym, bar, restaurant, pub and theatre), on board a cruise ship voyaging across the UK and EU, with the study conducted in the framework of the EU HEALTHY SAILING project.