Rare genetic diseases are difficult to diagnose and this translates in patient's diagnostic odyssey! This is particularly true for more than 900 rare diseases including orodental developmental anomalies such as missing teeth. However, if left untreated, their symptoms can become significant and disabling for the patient. Early detection and rapid management are therefore essential in this context.
View Article and Find Full Text PDFMicroarray experiments, a mainstay in gene expression analysis for nearly two decades, pose challenges due to their complexity. To address this, we introduce DExplore, a user-friendly web application enabling researchers to detect differentially expressed genes using data from NCBI's GEO. Developed with R, Shiny, and Bioconductor, DExplore integrates WebGestalt for functional enrichment analysis.
View Article and Find Full Text PDFThe estimation of visibility is of significant importance in aviation safety and forms part of the measurements routinely collected in real time to provide safety guidelines and decisions. Our work concerns the creation and implementation of a lidar-based visibility estimation system as part of the SAFETRANS research program. We created a reproducible system to (1) support standard airport equipment, (2) serve simultaneously as a visibility meter and a ceilometer reporting on cloud cover, (3) offer increased accuracy and improved capabilities compared to standardized equipment currently in use while (4) requiring minimal user training to function.
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