Proton radiotherapy as an alternative to exenteration in the management of extended conjunctival melanoma.

Background: Diffuse and multifocal patterns of conjunctival melanoma may not be treatable with standard eye-sparing methods. The purpose of this study was to evaluate the usefulness of proton beam radiation therapy as an alternative to exenteration.

Methods: Twenty patients with extended conjunctival melanoma were treated by proton beam irradiation.

Do different osmolar solutions change the epithelial surface of the healthy rabbit cornea?

Background: We evaluated various osmolar solutions in use for ophthalmic treatment for their effect on the corneal surface. Healthy corneas were exposed to hypoosmolar balanced salt solution (BSS), an isoosmolar solution and hyperosmolar solution Previn.

Methods: Rinsing solutions--BSS from Opsia, and Previn from Prevor--were provided by the manufacturers.