A Pilot Randomized Controlled Trial of Families Addressing Cancer Together for Parents With Cancer: Feasibility, Acceptability, and Preliminary Effects.

Objective: To evaluate the feasibility, acceptability, and preliminary efficacy of Families Addressing Cancer Together (FACT), a web-based, individually tailored, psychoeducational intervention for parents with cancer to improve illness-related communication with their minor children.

Methods: Parents with stage I-IV solid tumors who had children ages 3-17 were randomized to 6 weeks of FACT versus waitlist control. Feasibility was assessed by rates of recruitment and retention.

Altered gene expression profiling by non-thermal plasma-activated media treatment in radioresistant head and neck squamous cell carcinoma.

Objective: High recurrence rates in head and neck squamous cell carcinoma (HNSCC) significantly affect prognosis, especially in radioresistant HNSCC (RR-HNSCC). Nonthermal plasma (NTP) therapy can effectively suppress the progression of HNSCC; however, the therapeutic mechanism of NTP therapy for RR-HNSCC remains unclear. In this study, we investigated the regulatory role of NTP in the RR-HNSCC signaling pathway and identified its signature genes.

Association between genetically predicted leisure and social activities and cardiovascular disease and other health outcomes.

Participation in leisure and social activities (LSA) is associated with better health outcomes and lower mortality. Previous observational studies demonstrated a relationship between engagement in LSA and both mental and physical health. Although several studies examined the association between LSA and health outcomes, including cardiovascular disease, their possible causal relationship has not been studied.

The association between acute transverse myelitis and COVID-19 vaccination in Korea: Self-controlled case series study.

Background: Acute transverse myelitis (ATM) has been reported as a potential association between COVID-19 vaccination. In this study, we aimed to investigate the association between the COVID-19 vaccination and ATM.

Methods: A self-controlled case series study was performed using a large database that combine the COVID-19 vaccine registry and the national claims database.

Widespread admixture blurs population structure and confounds Lake Trout (Salvelinus namaycush) conservation even in the genomic era.

Intraspecific variation is important for species' long-term persistence in changing environments. Conservation strategies targeting intraspecific variation often rely on the identification of management or policy units below the species level based on biological differences among populations. To identify management units, this paper examines intraspecific divergence of Lake Trout (Salvelinus namaycush) in Great Slave Lake (GSL), Canada, using low-coverage whole-genome sequencing data.