Publications by authors named "H Wakisaka"

An 86-year-old female was taken to hospital with complaints of general malaise and anorexia. Echocardiography showed an abnormal space between the ventricles, extending to the back of the left atrium, with a shunt from the left ventricle into both that abnormal space and the right ventricle. The next morning, the patient had a large amount of tarry stool and progressive anemia.

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Objectives: Brain-protective strategies for acute type A aortic dissection (TAAD) remain controversial. Moderate hypothermia circulatory arrest (MHCA) without cerebral perfusion is not commonly used. However, we aimed to assess its safety and efficacy in 358 patients who underwent hemiarch replacement with MHCA for acute type A aortic dissection at our institution from August 2012 to August 2022.

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Unlabelled: We report a case of a 45-year-old man presenting with tachycardia and palpitation. Echocardiography indicated severe tricuspid regurgitation. We suspected traumatic tricuspid damage due to high energy trauma in a motor vehicle accident 17 years earlier.

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Article Synopsis
  • PSAP (prosaposin) is a trophic factor primarily located in the basal side of seminiferous tubules, where Sertoli cells and pachytene spermatocytes are involved in its distribution and processing.
  • The PSAP-sortilin complex is targeted to large lysosomes in Sertoli cells for processing, while smaller lysosomes transport PSAP to the apical side for secretion around sperm heads.
  • In immature testis, PSAP is produced by tubular cells for self-proliferation, whereas in adults, both Sertoli cells and pachytene spermatocytes produce and secrete PSAP to support the proliferation and differentiation of surrounding germ cells.
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Objectives: Acute type A aortic dissection with coronary malperfusion syndrome is rare but associated with high mortality. Multi-organ malperfusion is an independent predictor of acute type A aortic dissection. Coronary malperfusion requires treatment, but it is not feasible to treat all malperfusions.

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