Publications by authors named "H Wafa"
Introduction: Annual screening for hydroxychloroquine (HCQ) retinopathy is recommended, and electroretinography (ERG) is considered a gold-standard test, but there are screening shortfalls and standard ERG is burdensome and has limited availability. Newer, portable ERG devices using skin-based electrodes may increase screening capacity but need validation. This study aims to determine initial device accuracies and feasibility of further research.
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- Choroidal metastasis from renal cell cancer (RCC) is extremely rare, often presenting with sudden vision loss as the first symptom.
- A case involving a 52-year-old male with papillary RCC showed initial successful treatment, but he later developed vision issues attributed to metastases in various organs, including the eyes.
- The study emphasizes the importance of ophthalmologic examinations in RCC patients with unexpected vision changes, underscoring the need for awareness and documentation of these rare cancer manifestations to improve diagnosis and patient care.
Objective: This study aims to conduct a systematic review and meta-analysis of the diagnostic accuracy of deep learning (DL) using speech samples in depression.
Materials And Methods: This review included studies reporting diagnostic results of DL algorithms in depression using speech data, published from inception to January 31, 2024, on PubMed, Medline, Embase, PsycINFO, Scopus, IEEE, and Web of Science databases. Pooled accuracy, sensitivity, and specificity were obtained by random-effect models.
Background: Neovascular age-related macular degeneration (nAMD) is a leading cause of blindness. The first-line therapy is anti-vascular endothelial growth factor (anti-VEGF) agents delivered by intravitreal injection. Ionising radiation mitigates key pathogenic processes underlying nAMD, and therefore has therapeutic potential.
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- The study examines the effectiveness of targeted RNA-based sequencing (targeted RNA-seq) compared to traditional fluorescence in situ hybridization (FISH) for identifying gene fusions in soft tissue and bone tumors.
- Targeted RNA-seq found gene fusions in 35.9% of 131 samples and showed high negative concordance with FISH, but also detected cases that FISH missed.
- The research suggests that incorporating targeted RNA-seq into the diagnostic process improves accuracy and diagnosis in some cases, identifying four novel fusion transcripts whose clinical significance is still unknown.