Previous use of non-steroidal anti-inflammatory drugs and anticoagulants: the influence on clinical outcome of bleeding gastroduodenal ulcers.

Objective: To evaluate the relationship between prior non-steroidal anti-inflammatory drug (NSAID) or anticoagulant use and clinical outcome in bleeding gastric and duodenal ulcer patients.

Design: Prospective cohort-study.

Participants: All patients (n = 132) admitted because of upper gastrointestinal bleeding during 3 months in the Amsterdam area.