Publications by authors named "H W Helleman"
Introduction: Ototoxicity is an adverse effect of childhood cancer treatment with a negative impact on speech-language development and quality of life. This study aimed to retrospectively assess ototoxicity monitoring in a national cohort of pediatric patients with solid tumors, examining the frequency and determinants associated with hearing loss (HL).
Methods: This retrospective cohort study included 305 patients treated between 2015 and 2020 at the Princess Máxima Center.
Cochlear implants (CIs) restore hearing in patients with severe-to-profound deafness. Post-CI meningitis is a rare but redoubted complication. We present the case of a five-year-old CI recipient who experienced an episode of chronic meningitis caused by chronic otitis media with cholesteatoma encasing the electrode lead.
View Article and Find Full Text PDFObjective: To determine the benefit of sequential cochlear implantation after a long inter-implantation interval in children with bilateral deafness receiving their second implant between 5 and 18 years of age.
Study Design: Prospective cohort-study.
Setting: Tertiary multicenter.
Objective: Adolescents may be at risk of noise-induced hearing loss due to recreational sound. The aim of this study was to examine the role of distortion product otoacoustic emissions (DPOAEs) in screening for early stages of high-frequency loss such as can be observed in noise-induced hearing loss.
Setting And Design: This cross-sectional study was embedded within Generation R, an ongoing prospective birth cohort study in Rotterdam, The Netherlands.
Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report.
JAMA Oncol
October 2021
Article Synopsis
- Ototoxicity is a significant long-term effect of certain cancer treatments in children, making early detection and monitoring of hearing loss crucial for managing their overall care.
- The Ototoxicity Task Force, consisting of experts from various fields, developed standardized recommendations for monitoring hearing loss during pediatric cancer treatment.
- Key findings indicate that children undergoing ototoxic treatments should have regular hearing assessments, including baseline evaluations and ongoing monitoring throughout therapy, to ensure timely interventions when needed.