Publications by authors named "H W Folkerts"
Importance: Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider a broader clinical spectrum, disentangle illness trajectories, and investigate genetic associations.
Objective: To detect psychosis subgroups using data-driven methods and examine their illness courses over 1.
Cognitive deficits are a core feature of psychiatric disorders like schizophrenia and bipolar disorder. Evidence supports a genome-wide polygenic score (GPS) for educational attainment (GPS) can be used to explain variability in cognitive performance. We aimed to identify different cognitive domains associated with GPS in a transdiagnostic clinical cohort of chronic psychiatric patients with known cognitive deficits.
View Article and Find Full Text PDFVacuole membrane protein (VMP1) is a putative autophagy protein, which together with Beclin-1 acts as a molecular switch in activating autophagy. In the present study the role of VMP1 was analysed in CD34 cells of cord blood (CB) and primary acute myeloid leukemia (AML) cells and cell lines. An increased expression of VMP1 was observed in a subset of AML patients.
View Article and Find Full Text PDFBackground: Religious delusions are a common symptom in patients experiencing psychosis, with varying prevalence rates of religious delusions across cultures and societies. To enhance our knowledge of this distinct psychotic feature, we investigated the mutually-adjusted association of genetic and environmental factors with occurrence of religious delusions.
Methods: We studied 262 adult German patients with schizophrenia or schizoaffective disorder.