Galaxy clusters enveloped by vast volumes of relativistic electrons.

The central regions of galaxy clusters are permeated by magnetic fields and filled with relativistic electrons. When clusters merge, the magnetic fields are amplified and relativistic electrons are re-accelerated by turbulence in the intracluster medium. These electrons reach energies of 1-10 GeV and, in the presence of magnetic fields, produce diffuse radio halos that typically cover an area of  around 1 Mpc.

Influence of Serotonin 5-HT Receptors on Responses to Cardiac Stressors in Transgenic Mouse Models.

The current study aimed to deepen our knowledge on the role of cardiac 5-HT receptors under pathophysiological conditions. To this end, we used transgenic (TG) mice that overexpressed human 5-HT receptors solely in cardiac myocytes (5-HT-TG mice) and their wild-type (WT) littermates that do not have functional cardiac 5-HT receptors as controls. We found that an inflammation induced by lipopolysaccharide (LPS) was detrimental to cardiac function in both 5-HT-TG and WT mice.

Initial Characterization of Transgenic Mice Overexpressing Human Histamine H Receptors.

In an integrative approach, we studied the role of histamine H receptors in the mouse heart. We noted that histamine, added cumulatively to the organ bath, failed to affect the force of contraction in left atrial preparations and did not change spontaneous heart rate in right atrial preparations from wild-type mice. By contrast, in the same preparations from mice that overexpressed the human H receptor in a cardiac-specific way, histamine exerted concentration- and time-dependent positive inotropic and positive chronotropic effects.

[Psychosomatic aspects of diabetes mellitus in adolescence--a case report].

A case is reported of a 15-year-old girl with insulin-dependent diabetes mellitus and neurotic development. Emphasis is placed on psychosomatic considerations in the discussion of the disease in general and of crisis management and course of treatment in this particular case.