[Steroid drugs and GM-CSF modulates activity of Egr-1 in glioma cells].

Introduction: The Egr-1 protein is a transcriptional factor responsive to early growth. Transcriptional regulation of the promoter has been described like responsive to physical stress, osmotic changes, and cellular growth marker. However, there is no report about the pharmacological effect on the transcriptional regulation in gliomas.

[Quantitative analysis of worn and torn particles in periprosthetic tissue of hip and knee with scanning electron microscopy].

Background: Arthroplasty is successful because biocompatible material is available, but its lifespan decreases due to inadequate fixation, mechanical wear and tear, or biological loss caused by osteolysis. This last is a tissue response to wear particles of the implanted material localized in the bone--prosthesis interface. We undertook this study to present the morphological analysis and characterization of the metal wear particles (MWP) in the periprosthetic tissue of patients with prosthetic loosening.

Macropinocytosis is responsible for the uptake of pathogenic and non-pathogenic mycobacteria by B lymphocytes (Raji cells).

Background: The classical roles of B cells include the production of antibodies and cytokines and the generation of immunological memory, these being key factors in the adaptive immune response. However, their role in innate immunity is currently being recognised. Traditionally, B cells have been considered non-phagocytic cells; therefore, the uptake of bacteria by B cells is not extensively documented.

[Autosomal recessive limb-girdle muscular dystrophy].

Muscular dystrophies are a heterogeneous group of hereditary diseases characterized by loss of muscle and weakness of non neurogenic origin. They are caused by mutations in one or more genes involved in the formation of muscle cells. The discovery of several proteins in the muscle began with the discovery of dystrophin, 130 years after the clinical description of muscular dystrophy.

[Analysis of histological changes of tendinous grafts in reconstruction of the dorsal wrist ligament].

The reconstruction of the dorsal aspect of the triangular fibrocartilage complex in the distal radioulnar joint with an autologous ligament graft has been an optimal treatment for instability of this joint. Tendinous grafts for ligament reconstruction have been studied in ACL reconstruction finding a metaplasia of the tendinous tissue into ligament like tissue. These studies have been performed in humans without making an important lesion to the reconstructed ligament.