Publications by authors named "H Van Keulen"

Article Synopsis
  • COVID-19 emerged as a global pandemic in December 2019, leading to significant hospitalizations and deaths, and the development of non-mandatory vaccinations in the Netherlands aimed at empowering informed decision-making through reliable information.
  • An online COVID-19 vaccination decision aid (DA) was created following a user-centered design approach, involving three phases of development and feedback from end-users and experts to ensure accessibility and effectiveness for individuals with low literacy.
  • The DA was successfully developed in 14 weeks, featuring modules for information provision, decision support, and action facilitation, and was widely disseminated in May 2021, reaching a diverse audience across the Netherlands.
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Introduction: Maintaining and enhancing vaccine confidence continues to be a challenge. Making an informed decision not only helps to avoid potential future regret but also reduces susceptibility to misinformation. There is an urgent need for interventions that facilitate informed decision-making about vaccines.

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Article Synopsis
  • - The study developed and assessed a group-antenatal care intervention in the Netherlands to enhance informed decision-making about Maternal Pertussis Vaccination (MPV) among pregnant individuals.
  • - Interviews with participants and facilitators indicated that the intervention was well-implemented and perceived positively, though some found it time-consuming and had already decided on the vaccination.
  • - The findings suggest that integrating MPV discussions earlier in pregnancy could improve decision-making, and further research is needed to evaluate the intervention's effects on vaccination uptake.
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Article Synopsis
  • In 2019, maternal pertussis vaccination (MPV) was introduced in the Netherlands, and a study evaluated the impact of an online decision aid (DA) on informed decision making (IDM) and MPV uptake among pregnant individuals.
  • The randomized controlled trial involved 1,236 participants, with some receiving the DA and others not, measuring outcomes like MPV uptake and IDM at various stages of pregnancy.
  • While the overall MPV uptake was high (92.3%), the DA significantly improved participants' IDM and knowledge about MPV, but did not directly impact the actual vaccination uptake; increased DA use correlated with higher MPV uptake.
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Carbohydrates from polysaccharides in natural thermoset Anacardiaceae polymers of Gluta usitata, Toxicodendron succedaneum and Toxicodendron vernicifluum were identified using pyrolysis-gas chromatography-mass spectrometry with in situ trimethylsilylation. Pyrolysates resulting from the pyrolytic intermolecular chain scission of the polysaccharides were used to elucidate monomeric units. Polysaccharides, dispersed in the phenolic lacasse catalysed cross-linked macromolecules, showed to be metabolised through various catabolic and anabolic routes.

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