Acute stress and multicellular development alter the solubility of the Sup35 ortholog ERF3.

Among sequenced organisms, the genome of is unique in that it encodes for a massive amount of repeat-rich sequences in the coding region of genes. This results in the proteome encoding for thousands of repeat-rich proteins, with nearly 24% of the proteome encoding Q/N-rich regions that are predicted to be prion like in nature. To begin investigating the role of prion-like proteins in , we decided to investigate ERF3, the ortholog of the well-characterized yeast prion protein Sup35.

Evaluating the Use of ChatGPT to Accurately Simplify Patient-centered Information about Breast Cancer Prevention and Screening.

Purpose To evaluate the use of ChatGPT as a tool to simplify answers to common questions about breast cancer prevention and screening. Materials and Methods In this retrospective, exploratory study, ChatGPT was requested to simplify responses to 25 questions about breast cancer to a sixth-grade reading level in March and August 2023. Simplified responses were evaluated for clinical appropriateness.