Publications by authors named "H V Ulmer"
Background: Immune checkpoint inhibitors (ICIs) are an important therapeutic pillar in metastatic urothelial carcinoma (mUC). The occurrence of immune-related adverse events (irAEs) appears to be associated with improved outcomes in observational studies. However, these associations are likely affected by immortal time bias and do not represent causal effects.
View Article and Find Full Text PDFBackground: The amount of regular physical activity (PA) can modulate the prevalence of traditional risk factors for cardiovascular disease (CVD) such as obesity, systemic hypertension, hypercholesterolemia, and type 2 diabetes (T2D). However, how different PA levels either below (< 600 MET min/week), within (600-1200 MET min/week), or above (> 1200 MET min/week) the range of the minimal WHO recommendations impact the age- and sex-dependent prevalence of these risk factors remains to be elucidated.
Methods: This cross-sectional study was performed to evaluate these relationships using population-based self-reported data collected in a central European country (Austria, 2019).
Background: The impact of sex-differences on the release of cardiac biomarkers after coronary artery bypass grafting (CABG) remains unknown. The aim of our study was to (1) investigate the impact of sex-differences in cardiac biomarker release after CABG and (2) determine sex-specific thresholds for high-sensitivity cardiac troponin (hs-cTn) and creatine kinase-myocardial band (CK-MB) associated with 30-day major adverse cardiovascular events (MACE) and mortality.
Methods: A consecutive cohort of 3687 patients, comprising 643 women (17.
Article Synopsis
- Coagulopathy and organ dysfunctions are critical features of sepsis, and a study explored the role of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in septic shock patients.
- In the study, patients with septic shock had significantly higher levels of both TF and TFPI compared to healthy controls, with differences in their ratios possibly indicating disease severity and outcomes.
- The research findings suggest that a high TF/TFPI ratio is linked specifically to heart injury in septic patients, while elevated TFPI levels correlate with multiple organ dysfunctions and overall disease severity.