Publications by authors named "H V Curran"

Background: Lesbian, gay, bisexual, transgender and queer (LGBTQ+) young adults (YA) experience disparities in nicotine and tobacco use. Mass-reach health communications can prevent nicotine and tobacco initiation and progression, but LGBTQ+adults report low engagement. Although cultural targeting (CT) could reach LGBTQ+YA, we know little about the strategies that resonate with this population.

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Introduction: Young adults who are sexual and gender minorities (SGM) are at the highest risk for tobacco initiation in young adulthood. Minority stress theory suggests that sexual orientation and gender identity (SOGI)-based discrimination may contribute to nicotine and tobacco use disparities. Our study aimed to quantify the association between SOGI-based distal minority stressors and current tobacco use among SGM young adults living in the United States (US).

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Adolescence is a time of rapid neurodevelopment and the endocannabinoid system is particularly prone to change during this time. Cannabis is a commonly used drug with a particularly high prevalence of use among adolescents. The two predominant phytocannabinoids are Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which affect the endocannabinoid system.

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Article Synopsis
  • Many oral nicotine pouches (ONPs) use synthetic nicotine, which includes a mix of S-nicotine and R-nicotine, but most tobacco-derived nicotine is primarily S-nicotine, making R-nicotine's effects mostly unknown.
  • In a study involving 18 adult smokers, participants tested ONPs with more than 99% S-nicotine and racemic nicotine, measuring nicotine levels in their blood and product appeal after usage.
  • Results showed that ONPs with over 99% S-nicotine had significantly higher nicotine concentrations in the blood, although perceived product liking and withdrawal relief were similar across both types of ONPs, with some reporting more adverse effects from the S-nicotine pouches.
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Adolescence is a developmental period characterised by increased vulnerability to cannabis use disorder (CUD). However, previous investigations of this vulnerability have relied on cross-sectional comparisons and lack a detailed assessment of cannabis quantity, a potentially important confounding factor. Here, we aimed to investigate the one-year course of CUD in adolescents compared to adults who currently use cannabis, adjusting for a comprehensive measure of cannabis quantity.

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