Conformational analysis of lipid membrane mimetics modified with A peptide by Raman spectroscopy and computer simulations.

Peptide-lipid interactions play an important role in maintaining the integrity and function of the cell membrane. Even slight changes in these interactions can induce the development of various diseases. Specifically, peptide misfolding and aggregation in the membrane is considered to be one of the triggers of Alzheimer's disease (AD), however its exact mechanism is still unclear.

Density functional theory for doped TiO: current research strategies and advancements.

Since the inception of the density functional theory (DFT) by Hohenberg and Kohn in 1964, it rapidly became an indispensable theoretical tool across various disciplines, such as chemistry, biology, and materials science, among others. This theory has ushered in a new era of computational research, paving the way for substantial advancements in fundamental understanding. Today, DFT is routinely employed for a diverse range of applications, such as probing new material properties and providing a profound understanding of the mechanisms underlying physical, chemical, and biological processes.

Comparative Study of SERS-Spectra of NQ21 Peptide on Silver Particles and in Gold-Coated "Nanovoids".

The NQ21 peptide has relatively recently attracted attention in the biomedical sphere due to its prospects for facilitating the engineering of the HIV1 vaccine and ELISA test. Today, there is still a need for a reliable and fast methodology that reveals the secondary structure of this analyte at the low concentrations conventionally used in vaccines and immunological assays. The present research determined the differences between the surface-enhanced Raman scattering (SERS) spectra of NQ21 peptide molecules adsorbed on solid SERS-active substrates depending on their geometry and composition.

Polymer Membrane Modified with Photocatalytic and Plasmonic Nanoparticles for Self-Cleaning Filters.

In this study, we developed a filtering material for facial masks, which is capable of trapping and subsequent inactivation of bacteria under white light emitting diodes (LED) or sunlight irradiation. Such a functionality is achieved via the modification of the composite membrane based on porous polymer with photocatalytic (TiO) and plasmonic (Ag) nanoparticles. The porous polymer is produced by means of a computer numerical control machine, which rolls a photoresist/thermoplastic mixture into a ~20-µm-thick membrane followed by its thermal/ultraviolet (UV) hardening and porosification.