Publications by authors named "H Uuml Seyin Cihan Demirel"

Cisplatin (CIS) is a chemotherapeutic agent frequently used in cancer treatment. However, depending on the dosage and duration of use, CIS can lead to hepatotoxicity and nephrotoxicity. Iristectorin A (IRIS), a natural flavonoid, has been found to exhibit antioxidant and protective effects.

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Background: Biomaterials used in fracture healing hold a significant place in orthopedics. This study aimed to develop biomaterials coated with hydroxyapatite (HA), boric acid (BA), and magnesium (Mg) and investigate their effects on fracture healing.

Methods: Sixty female Wistar Albino rats were included in the study.

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  • Loneliness is a critical public health issue for older adults, influencing their physical and mental well-being; social support and health empowerment are key factors in addressing this problem.
  • The study involved 277 nursing home residents aged 65 and above to explore how health empowerment mediates the connection between social support and loneliness, finding a significant partial mediation effect.
  • The results suggest that enhancing health empowerment can help mitigate loneliness among seniors, highlighting the important role nurses play in supporting older adults through education and intervention strategies.
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  • The study looked at how magnolin (MAG) protects rats from damage caused by a drug called cyclophosphamide (CP).
  • When rats were given CP, it hurt their organs and increased harmful substances in their bodies.
  • Treatment with MAG helped improve these problems by reducing stress and inflammation in their bodies.
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Pyraclostrobin, a strobilurin-derived fungicide, causes oxidative stress and DNA damage in the organism. Taurine plays an important role in metabolic processes such as osmoregulatory, cytoprotective, and antioxidant effects. The study aimed to investigate the protective effect of taurine in Sprague Dawley male rats exposed to pyraclostrobin.

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