Glucose transporter 1 in vascular smooth muscle cells is dispensable for abdominal aortic aneurysm induced by angiotensin II.

Treatment with an inhibitor of glucose use via glucose transporters (GLUT) has been shown to attenuate experimental abdominal aortic aneurysm (AAA) development in mice. Vascular smooth muscle cell (VSMC) signaling seems to be essential for angiotensin II (Ang II)-induced AAA in mice. Accordingly, we have tested a hypothesis that VSMC silencing of the major GLUT, GLUT1, prevents AAA development and rupture in mice treated with Ang II plus β-aminopropionitrile.

Biomonitoring Metal Pollution in a Reservoir and River in Brazil Using Bullfrog Tadpoles' Tissues and Biomarkers.

Bullfrog tadpoles were exposed (96 h) to water from two sites (the Ibiúna and the Itupararanga reservoir) on the Sorocaba River (São Paulo, Brazil). Metal concentrations (Ba, Cu, Mn, Sr and Zn) and metallothioneins (MTs) levels were determined in the gills (n = 27) and caudal muscle (n = 18). Metals increased in the gills of the animals exposed to the waters of the Sorocaba River in relation to the control and in relation to the animals exposed to the waters of the Ibiúna point.

Use of biomarkers in bullfrog tadpoles Aquarana catesbeiana (Shaw 1802) for ecotoxicological evaluation of Pirajibú River (São Paulo, Brazil).

This study focused on investigating the water quality in the Pirajibú River, a relevant water body that flows through the industrial zone of Sorocaba (São Paulo/Brazil). Due to the limitations of assessing water quality based solely on standard physicochemical tests, an ecotoxicological approach was used to assess biomarker changes in the liver of bullfrog tadpoles (Aquarana catesbeiana). The animals were divided into groups and exposed to water samples collected upstream and downstream of the industrial zone.

Associations of ocular anterior segment structures with sex and age: the Yamagata study (Funagata).

Purpose: To investigate the associations of tomographic parameters in anterior segment optical coherence tomography (AS-OCT) with sex and age in a cohort study.

Study Design: A cohort design.

Materials And Methods: AS-OCT data from 391 Japanese participants aged ≥ 35 years were obtained using swept-source OCT.