Search for Magnetic Monopole Pair Production in Ultraperipheral Pb+Pb Collisions at sqrt[s_{NN}]=5.36 TeV with the ATLAS Detector at the LHC.

This Letter presents a search for highly ionizing magnetic monopoles in 262  μb^{-1} of ultraperipheral Pb+Pb collision data at sqrt[s_{NN}]=5.36  TeV collected by the ATLAS detector at the LHC. A new methodology that exploits the properties of clusters of hits reconstructed in the innermost silicon detector layers is introduced to study highly ionizing particles in heavy-ion data.

The dynamical Ising-Kac model in 3 converges to .

We consider the Glauber dynamics of a ferromagnetic Ising-Kac model on a three-dimensional periodic lattice of size , in which the flipping rate of each spin depends on an average field in a large neighborhood of radius . We study the random fluctuations of a suitably rescaled coarse-grained spin field as and ; we show that near the mean-field value of the critical temperature, the process converges in distribution to the solution of the dynamical model on a torus. Our result settles a conjecture from Giacomin et al.

Implementing a Neurology Mentorship Program to Ease Residency Application Process (P1-7.008).

Objective: To describe the implementation and outcomes of a structured neurology mentorship program to assist senior medical students applying into neurology residency programs.

Background: Medical students regard mentorship as an important component of their medical education; however, only approximately one-third of medical students report having a mentor. This highlights a significant gap and need for formal mentorship programs in medical education, particularly in neurology.

Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a pan-degrader.

Proteolysis-targeting chimeras (PROTACs) have recently gained popularity as targeted protein degradation (TPD) promises to overcome the limitations of occupancy-driven pharmacology. However, most degraders rely on a small number of E3 ligases. In this study, we present the first-in-class histone deacetylase (HDAC) PROTACs recruiting the DDB1- and CUL4- associated factor 11 (DCAF11).

Irritable bowel syndrome, the gut microbiome, and diet.

Purpose Of Review: To provide an update of recent studies exploring the role of the gut microbiota and diet in the pathogenesis and treatment of irritable bowel syndrome (IBS).

Recent Findings: The human gut microbiome has been recognized as an important, active source of signaling molecules that explain in part the disorder of the gut brain interaction (DGBI) in IBS. Subsequent changes in the metabolome such as the production of short-chain fatty acids (SCFA) and serotonin are associated with IBS symptoms.