Publications by authors named "H U Naegeli"
Article Synopsis
- Assisted reproductive technologies in equine reproduction show low success with conventional IVF, emphasizing the importance of the 'cumulome' related to oocyte development.
- A total of 1671 proteins and 612 metabolites were analyzed from cumulus-oocyte complexes, comparing immature and matured oocytes through various stages of development.
- Findings indicate that the mature oocyte groups have enhanced energy metabolism and vesicular transport pathways, while immature oocytes show different protein profiles related to extracellular matrix composition and lower ATP-related compounds.
Genetically modified (GM) maize DP910521 was developed to confer resistance against certain lepidopteran insect pests as well as tolerance to glufosinate herbicide; these properties were achieved by introducing the expression cassettes. The molecular characterisation data and bioinformatic analyses did not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize DP910521 and its conventional counterpart needs further assessment except for the levels of iron in grain, which do not raise safety and nutritional concerns.
View Article and Find Full Text PDFGenetically modified maize MON 95275 was developed to confer protection to certain coleopteran species. These properties were achieved by introducing the , and expression cassettes. The molecular characterisation data and bioinformatic analyses reveal similarity to known toxins, which was further assessed.
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- - EFSA was asked by the European Commission to evaluate the safety and regulation of new biotech developments (NGTs) applied to microorganisms for environmental release and food/feed use.
- - A study found that NGT-modified microorganisms are not expected to pose new risks compared to those modified through older genetic methods, suggesting NGTs might lead to fewer hazards overall.
- - EFSA's existing guidelines are deemed "partially applicable," meaning some aspects can be simplified for NGTs, but updates are needed for better risk assessment across all genetic modification methods.
EFSA was asked by the European Parliament to provide a scientific opinion on the analysis by the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) of Annex I of the European Commission proposal for a regulation 'on plants obtained by certain new genomic techniques (NGTs) and their food and feed, and amending regulation (EU) 2017/625'. The Panel on genetically modified organisms (GMO) assessed the opinion published by ANSES, which focuses on (i) the need to clarify the definitions and scope, (ii) the scientific basis for the equivalence criteria and (iii) the need to take potential risks from category 1 NGT plants into account. The EFSA GMO Panel considered the ANSES analysis and comments on various terms used in the criteria in Annex I of the European Commission proposal and discussed definitions based on previous EFSA GMO Panel opinions.
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