Publications by authors named "H U Hongyi"
Article Synopsis
- The study aimed to assess the effectiveness and safety of Buzhongyiqi pills (BZYQP) in enhancing the appetite of colorectal cancer patients undergoing chemotherapy.
- A randomized, single-blind trial involved 62 stage II-IV colorectal cancer patients divided into two groups, alternating between BZYQP and a placebo before and after chemotherapy cycles.
- Results showed that the group taking BZYQP had significantly better appetite scores initially, but their appetite decreased after the washout period, highlighting the treatment's impact during the early chemotherapy phases.
Background: Parkinson's disease (PD) is the second most common neurodegeneration disease worldwide. Necroptosis, which is a new form of programmed cell death with high relationship with inflammation, plays a vital role in the progression of PD. However, the key necroptosis related genes in PD are not fully elucidated.
View Article and Find Full Text PDFThe effects of VEGFA isoforms on the vascular permeability and structure are still unclear. In this study, we found that VEGFA121 and VEGFA165, 2 isoforms of VEGFA, exerted the opposing effects of antiangiogenesis and proangiogenesis on regulating vascular endothelia cells proliferation and tube formation. The 2 isoforms affected the protein expression of Ras-related protein 1-GTPase-activating protein 1 (Rap1GAP) and thrombospondin 1, 2 important signal molecules of Rap1GAP/thrombospondin 1 signal pathway in primary human umbilical vein endothelial cells by regulating 2 different phosphorylating sites of VEGFR2, Tyr(1175) and Tyr(1214).
View Article and Find Full Text PDF