Publications by authors named "H Tufa Tesfaye"
Empagliflozin and the Risk of Retinopathy in Patients With Type 2 Diabetes.
JAMA Ophthalmol
December 2024
Article Synopsis
- Empagliflozin may reduce the risk of diabetic retinopathy (DR) by preventing the loss of retinal pericytes, but its effectiveness compared to DPP4 inhibitors in patients with type 2 diabetes (T2D) is not well established.
- A study was conducted using U.S. insurance claims data from 2014 to 2019, focusing on adults with T2D who were newly prescribed either empagliflozin or a DPP4 inhibitor, and looking at the incidence of nonproliferative DR and its progression.
- Results showed that among matched patient pairs, empagliflozin's impact on the rates of incident DR and progression was analyzed, with significant data collected over an average
Culicoides, among the tiniest and most abundant hematophagous insects globally, serve as vectors for a variety of pathogens such as viruses, bacteria, parasites, protozoa, and nematodes. This study aimed to identify Culicoides species and assess their spatial distribution and seasonal occurrence in selected districts of the Central, South, and West Gondar zones, Northwest Ethiopia. A cross-sectional study was conducted between January to July 2023.
View Article and Find Full Text PDFArticle Synopsis
- * In these studies, treatment groups were well-matched and larger than in traditional trials, providing more robust comparisons of treatment outcomes.
- * The results showed discrepancies between observational findings and randomized trials, potentially due to treatment discontinuations that cannot be replicated in observational settings.
Background: Venous thromboembolism (VTE) remains the commonest preventable cause of death in postoperative patients. VTE prophylaxis significantly reduces mortality risk, yet its utilization remains alarmingly low and variable (6-61 %) worldwide. This study aimed to compare VTE prophylaxis use among adult surgical patients in major hospitals in Addis Ababa, Ethiopia.
View Article and Find Full Text PDFObjective: We compared health care resource utilization (HCRU) and costs for inpatient and outpatient services and dispensed medications in older adults with type 2 diabetes initiating empagliflozin versus dipeptidyl peptidase 4 inhibitors (DPP-4is).
Research Design And Methods: The study population included U.S.