Publications by authors named "H Tsuru"
Background: The Esophageal Hypervigilance and Anxiety Scale (EHAS) is an English questionnaire created in the USA to assess these factors in all patients with esophageal diseases. The aim of this study was to develop and validate the Japanese version of EHAS and investigate the relationship between EHAS scores and symptoms in untreated disorders of esophagogastric junction (EGJ) outflow.
Methods: This prospective study recruited patients who underwent high-resolution manometry (HRM) at six tertiary centers in Japan.
Article Synopsis
- This study focuses on reflux hypersensitivity (RH), a severe form of gastroesophageal reflux disease, specifically looking at how an advanced endoscopy system can help assess duodenogastroesophageal reflux (DGER).
- Researchers tested a special imaging mode (Bil mode) for visibility of bilirubin and compared its effectiveness against traditional imaging techniques, finding it significantly superior for certain concentrations.
- Results indicated that higher bilirubin levels in the esophagus correlate well with nonacid reflux events, suggesting that the Bil mode could be an effective tool for diagnosing RH in patients.
Down syndrome (DS) is the most prevalent chromosomal disorder associated with a higher incidence of pulmonary arterial hypertension (PAH). The dysfunction of vascular endothelial cells (ECs) is known to cause pulmonary arterial remodeling in PAH, although the physiological characteristics of ECs harboring trisomy 21 (T21) are still unknown. In this study, we analyzed the human vascular ECs by utilizing the isogenic pairs of T21-induced pluripotent stem cells (iPSCs) and corrected disomy 21 (cDi21)-iPSCs.
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