[Tunneled femoral catheters of long duration].

The femoral vascular access may be the only alternative when the upper limbs venous capital is exhausted. Five patients benefited from the setting up of a tunneled femoral catheter, for a median period of three months (three months minimum, eleven months maximum). No early complication has been observed.

[Autosomal dominant polycystic kidney and genetic markers of chromosome 16].

The mutation for autosomal dominant polycystic kidney disease (APKD) has been mapped by linkage analysis on the distal part of the short arm of chromosome 16. We present in this study the results of linkage analysis using the two most tightly linked DNA markers (3'HVR and 24-1) in 183 members of 14 families of a same ethnic origin. We have constructed haplotypes using these two polymorphic probes, and compared the frequency of these on the normal and the affected chromosome.

[The lung in monocional gammapatheis. Alternative hypotheses coming from a privileged observation (association of a diffuse interstitial fibrosis to a pulmonary tuberculosis then a disease of heavy gamma chains) (author's transl)].

The observation of a 61 year old woman who had a diffuse interstitial fibrosis, a pulmonary tuberculosis and a disease of heavy gamma chains is reported here. The different tumoral and infectious pneumopathies during monoclonal gammapathies are analyzed. In the opposite, there are the various abnormalities observed in thoracic pathology: chronic infections, pulmonary tuberculosis and diffuse interstitial fibrosis.