Dystonia is often associated with functional alterations in the cerebello-thalamic pathways, which have been proposed to contribute to the disorder by propagating pathological firing patterns to the forebrain. Here, we examined the function of the cerebello-thalamic pathways in a model of DYT25 dystonia. DYT25 () mice carry a heterozygous knockout mutation of the gene, which notably disrupts striatal function, and systemic or striatal administration of oxotremorine to these mice triggers dystonic symptoms.
View Article and Find Full Text PDFArtificial intelligence is based on algorithms that enable machines to make decisions instead of humans. This technology improves user experiences in a variety of areas. In this paper we discuss an intelligent solution to predict the performance of Moroccan students in the region of Guelmim Oued Noun through a recommendation system using artificial intelligence techniques during the COVID-19.
View Article and Find Full Text PDFMycoplasma meleagridis (MM) is a major cause of disease and economic loss in turkeys. Formerly it was thought that this species was very host specific and only restricted to turkey. In this study, we report on the recovery of MM from breeding flocks of chickens located near a turkey breeding unit.
View Article and Find Full Text PDFAim: To determine the prevalence of antibodies to hepatitis C virus (HCV) in a cohort of patients infected with human immunodeficiency virus 1 (HIV-1) and to compare risk factors.
Methods: Multicenter retrospective study from infectious diseases department in Tunisia. We examined sera from HIV patients followed in these centers.