Publications by authors named "H Toosa"

Article Synopsis
  • A system was developed to display antigens from Enterovirus type 71 (EV71) on the surface of Lactococcus lactis for potential use as an oral vaccine.
  • The viral capsid protein (VP1) gene was used to create fusion proteins, which were expressed in E. coli and then introduced to L. lactis.
  • Mice fed with L. lactis displaying these proteins showed an immune response, marking this as the first instance of an EV71 antigen on a food-grade organism, which may lead to new vaccine strategies and flexible protein presentations using L. lactis.
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Enterococcus species isolated from poultry sources were characterized for their resistance to antibiotics, plasmid content, presence of van genes and their diversity by randomly amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR). The results showed that all isolates were multi-resistance to the antibiotics tested. Ampicillin (15/70) followed by chloramphenicol (37/70) were the most active antibiotics tested against the Enterococcus spp.

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Twenty-eight isolates of E. faecalis and 5 isolates of E. hirae were isolated from chicken samples obtained from markets in Sri Serdang, Selangor.

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