Publications by authors named "H Tokgoz"

Background: Intracranial hemorrhage (ICH) is reportedly rare but has high morbidity and mortality risk in persons with hemophilia. Although the risk factors that facilitate bleeding are known, the factors affecting the sequelae are not well known.

Objectives: We planned to investigate the risk factors for neurologic sequelae in children and adolescents with hemophilia suffering from ICH.

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Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

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Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease, with a high mortality if left untreated. In addition, the disease has unique diagnostic challenges. Therefore, despite the existing guidelines on management, current clinical practice data is informative on the course and outcome.

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Article Synopsis
  • Acute pulmonary embolism (PE) poses a significant risk of death in patients with active cancer; this study examines how cancer affects treatment choices and outcomes.
  • Out of 872 examined PE patients, 14.8% had active malignancy, with varying treatment approaches and poorer long-term outcomes for those with cancer.
  • Despite higher mortality rates and challenges, catheter-based treatments show promise for effectively managing PE in cancer patients while maintaining manageable bleeding risks.
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  • During the COVID-19 pandemic lockdown, the study assessed respiratory viral infections in children with cancer, highlighting their clinical impact.
  • Of the 265 episodes evaluated, human rhinovirus/enterovirus was the most common pathogen identified, with significant complications noted, including a higher rate of lower respiratory tract infections.
  • The findings emphasize the necessity for quicker detection and treatment of respiratory viruses to prevent severe outcomes in this vulnerable population.
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