Publications by authors named "H Tissot-Dupont"
During the current global outbreak of mpox (formerly monkeypox), atypical features were frequently described outside endemic areas, raising concerns around differential diagnosis. In this study, we included 372 adult patients who had clinical signs consistent with mpox and who were screened using non-variola orthopoxvirus specific quantitative polymerase chain reaction (PCR) between 15 May and 15 November 2022 at the University Hospital Institute Méditerranée Infection, Marseille, France. At least one clinical sample was positive for 143 (38.
View Article and Find Full Text PDFDuring the COVID-19 pandemic, patient care was mainly organized around the hospital. Pre-hospital care has, to our knowledge, never been evaluated. We aimed to study the impact of pre-hospital pathways on hospitalization during the last part of the pandemic.
View Article and Find Full Text PDFArticle Synopsis
- A significant outbreak of Monkeypox virus (MPXV) was reported in nonendemic countries starting in May 2022, leading to a study of clinical samples from infected patients between June and July 2022.
- Using advanced DNA metagenomics and sequencing technologies, researchers classified the genomes of MPXV from 18 patients, finding a high number of mutations compared to previous strains, specifically in clade IIb, lineage B.1.
- The study highlighted the role of specific mutations in crucial viral genes and recommended enhanced genomic and clinical monitoring of MPXV and related bacterial infections in patients to better understand the virus's evolution and infection complications.