Publications by authors named "H Thamizhchelvan"

Background: Oral cancer; categorised under head and neck cancers (HNC) predominantly originates from squamous cells and is referred as oral squamous cell carcinoma (OSCC). Various factors (internal and external) causes OSCC. PI3K/AKT/mTOR pathways are known to be primarily mutated in HNC.

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Melanoma is the ninth most prevalent and the second most lethal tumour. The aetiology and pathogenesis remain uncertain. It occurs in elderly people, over the fifth decade, and is predominant in males.

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Hemangiomas are hamartomatous benign tumours of the vascular tissue, which are common among infants and adolescents and are found in the head and neck region. Oral hemangiomas are infrequently encountered in the palate. Baseline soft tissue imaging must be considered for an appropriate diagnosis and treatment approach.

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Article Synopsis
  • * It explores the tumor microenvironment (TME), which includes various cells and components that contribute to cancer progression, metastasis, and immune evasion.
  • * Key tissue biomarkers (e.g., mTOR, CAF, FOXp3) associated with TME are highlighted as potential therapeutic targets currently being studied in clinical trials.
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Superficial mucoceles are benign, small, translucent vesicles occurring in any part of the oral cavity, due to extravasation of saliva due to ruptured minor salivary gland ducts. This distinct entity presents as single or multiple asymptomatic vesicles. The etiology is unclear; however, these are not associated with a history of trauma, unlike the conventional mucoceles.

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