Barriers and facilitators to implementing polypharmacy management frameworks: a theory based qualitative exploration of key stakeholders.

Background: Inappropriate polypharmacy arises through many factors including deficiencies in prescribing processes. Most research has focused on solutions at the clinician/patient levels with less at the organisational level.

Aim: To explore key stakeholder identified barriers and facilitators to implementation of an organisational level polypharmacy management framework.

Exploring determinants of antimicrobial prescribing behaviour using the Theoretical Domains Framework.

Background: Few theoretically-based, qualitative studies have explored determinants of antimicrobial prescribing behaviour in hospitals. Understanding these can promote successful development and implementation of behaviour change interventions (BCIs).

Objective: (s): To use the Theoretical Domains Framework (TDF) to explore determinants of clinicians' antimicrobial prescribing behaviour, identifying barriers (i.

T cell receptor excision circles (TRECs) and kappa-deleting recombination excision circles (KRECs) as markers of early T cell and B cell immune recovery after haematopoietic stem cell transplantation (HSCT).

Hematopoietic stem cell transplantation (HSCT) is a key therapeutic strategy for a number of hematological malignancies and non-malignant disorders of the hematopoietic system. One of the most important events post SCT is the immune system reconstitution-a process characterized by a considerable dynamic and is critical in promoting overall survival of transplant patients, restoring immune protection from opportunistic infections, and mediating an alloreactive graft-versus-tumor effect against residual malignant disease. T cell receptor excision circles (TRECs) and Kappa deleting recombination excision circles (KRECs) are byproducts of T cells and B cells receptor recombination processes, respectively and can be used in monitoring denovo synthesis of T cells and B cells post SCT.

Investigating clinicians' determinants of antimicrobial prescribing behaviour using the Theoretical Domains Framework.

Aim: To identify and quantify potential determinants of antimicrobial prescribing behaviour, using the Theoretical Domains Framework (TDF).

Methods: A cross-sectional survey involving doctors (∼4000) and pharmacists (∼400) working within Hamad Medical Corporation (HMC), Qatar. An online questionnaire, developed with reference to the TDF, included: personal and practice demographics, and Likert statements on potential determinants of antimicrobial prescribing practice.