Cytotoxic anticancer drug solution eye drops can hinder the cell division of corneal basal cell division and corneal limbal epithelial stem cell migration. We discuss a case involving recurrent corneal epithelial erosions induced by 1% 5-fluorouracil (5-FU) solution eye drops. A 68-year-old male with conjunctival papilloma on his left eye underwent recurrences three times and additional tumor excision.
View Article and Find Full Text PDFThe Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and Frontal Assessment Battery are screening tests for dementia. The go/no-go task offers an alternative approach for evaluating dementia patients. However, its role in screening for dementia remains unclear.
View Article and Find Full Text PDFBackground: Surgical errors in ophthalmology can have devastating consequences. We developed an artificial intelligence (AI)-based surgical safety system to prevent errors in patient identification, surgical laterality and intraocular lens (IOL) selection. This study aimed to evaluate its effectiveness in real-world ophthalmic surgical settings.
View Article and Find Full Text PDFSebaceous carcinoma is difficult to distinguish from chalazion due to their rarity and clinicians' limited experience. This study investigated the potential of AI-generated image training to improve diagnostic skills for these eyelid tumors compared to traditional video lecture-based education. Students from Orthoptics, Optometry, and Vision Research (n = 55) were randomly assigned to either an AI-generated image training group or a traditional video lecture group.
View Article and Find Full Text PDFBackground: To establish simple screening tests to suspect Alzheimer's disease (AD) pathology, the clinical sign "head-turning sign" (HTS), which is a patient's behavior of turning their head towards their partner to seek assistance with questions posed by the examiner during the interview, and the simple screening questionnaire for dementia named "Neucop-Q" were validated in participants diagnosed with amyloid and tau positron emission tomography (PET).
Methods: We enrolled 155 patients: 47 cognitive normal, 36 with mild cognitive impairment, 64 with dementia, and 8 with psychiatric disorders. All participants underwent Neucop-Q [three questions: Consciousness/self-awareness of cognitive disabilities (C) normal/impaired (nor/imp), Pleasure/pastime (P) nor/imp, and News/knowledge on current topics (N) nor/imp] and amyloid/tau PET.