The role of socioeconomic factors in sex differences in intrinsic capacity among older adults: A cross-sectional study in Taiwan.

Objectives: The World Health Organization's Integrated Care for Older People (ICOPE) framework launched in 2019 is used to assess the intrinsic capacity of older individuals. Older women may face greater socioeconomic disadvantages, which can impact their physical and mental well-being. Therefore, we examined sex differences in intrinsic capacity and the influence of socioeconomic status.

Influencing factors and prediction model construction for recurrence in patients with ovarian endometriosis after laparoscopic conservative surgery.

Objective: To investigate the factors influencing recurrence following laparoscopic conservative surgery in patients with ovarian endometriosis (OEM) and to develop a predictive model.

Methods: In this retrospective study, the clinical data from 212 OEM patients who underwent laparoscopic conservative surgery at Suzhou Ninth People's Hospital from May 2013 to December 2021 were meticulously reviewed. According to disease recurrence over a 2-year follow-up period, the patients were divided into a recurrence group and a non-recurrence group.

Molecularly manipulating pyrazinoquinoxaline derivatives to construct NIR-II AIEgens for multimodal phototheranostics of breast cancer bone metastases.

Multimodal phototheranostics on the basis of single molecular species shows inexhaustible and vigorous vitality, particularly those emit fluorescence in the second near-infrared window (NIR-II), the construction of such exceptional molecules nonetheless retains formidably challenging. In view of the undiversified molecular skeletons and insufficient phototheranostic outputs of previously reported NIR-II fluorophores, herein, electron acceptor engineering based on heteroatom-inserted rigid-planar pyrazinoquinoxaline was manipulated to fabricate aggregation-induced emission (AIE)-featured NIR-II counterparts with donor-acceptor-donor (D-A-D) architecture. Systematical investigations substantiated that one of those synthesized AIE molecules, namely 4TPQ, incorporating a fused thiophene acceptor, synchronously exhibited high molar absorptivity (ε), NIR-II emission, typical AIE tendency, significant reactive oxygen species (ROS) generation, and high photothermal conversion efficiency.

Prognostic Value of D-Dimer in Acute Type A Aortic Dissection and Intramural Hematoma: Observations from the Acute Aortic Syndrome Group of the Registry of Acute Non-Traumatic Chest Pain in China.

Background: Acute type A aortic dissection (AAD) and acute type A intramural hematoma (AIMH) are life-threatening conditions with high mortality rates, and prognostic indicators are critical for guiding urgent treatment decisions. We assessed the prognostic significance of admission D-dimer levels in patients with AAD and AIMH.

Methods And Results: The prospective, multicenter, observational study in China recruited participants from 2013 to 2019.

Monte Carlo-based realistic simulation of optical coherence tomography angiography.

Optical coherence tomography angiography (OCTA) offers unparalleled capabilities for non-invasive detection of vessels. However, the lack of accurate models for light-tissue interaction in OCTA jeopardizes the development of the techniques to further extract quantitative information from the measurements. In this manuscript, we propose a Monte Carlo (MC)-based simulation method to precisely describe the signal formation of OCTA based on the fundamental theory of light-tissue interactions.