Publications by authors named "H T Jacobe"
Introduction: Primary care providers or clinicians (PCPs) have the potential to assist dermatologists in screening patients at risk for skin cancer, but require training to appropriately identify higher-risk patients, perform skin checks, recognize and biopsy concerning lesions, interpret pathology results, document the exam, and bill for the service. Very few validated dermatology training programs exist for PCPs and those that are available focus primarily on one emphasis area, which results in variable efficacy and single-topic limited scope.
Methods: We have created a free, online, continuing education program (Melanoma Toolkit for Early Detection, MTED) that allows learners to choose from a variety of multimedia tools (image recognition, videos, written material, in-person seminars, self-tests, etc.
Article Synopsis
- - Localized scleroderma (LS) is an autoimmune disease that causes skin inflammation and fibrosis, leading to symptoms like hardening and discoloration of the skin, which can result in disability.
- - This study utilized single-cell RNA sequencing (scRNA-seq) to analyze skin cells from 27 LS patients and 17 healthy controls, focusing primarily on endothelial cells due to their known role in a related condition, systemic sclerosis (SSc).
- - The analysis identified eight subclusters of endothelial cells, with certain pathways upregulated in LS, suggesting these cells may contribute to disease progression and associated skin abnormalities.
Licensed nonmedical, skin-aware professionals (e.g., hairdressers, massage therapists, etc.
View Article and Find Full Text PDFPatients with autoimmune skin diseases are at increased risk of adverse pregnancy outcomes.
Am J Obstet Gynecol MFM
January 2024
Background: Increased rates of adverse pregnancy outcomes have been reported in association with rheumatologic diseases such as systemic lupus erythematosus, rheumatoid arthritis, dermatomyositis. However, little is known about pregnancy outcomes in patients with autoimmune skin diseases.
Objective: This study aimed to determine the frequency of adverse pregnancy outcomes in patients with autoimmune skin diseases.