Aim: The aim of the study was to evaluate and compare the cytotoxicity of 25% of neem leaf extract (), 20% of guava leaf extracts (), and 20% of cinnamon extract () irrigants at three intervals of time.
Methodology: Four groups were formed ( = 15), Group 1 (control group) - normal saline solution, Group 2 - 25% of neem extract, Group 3 - 20% of guava extract, and Group 4 - 20% of cinnamon extract. Each group was further divided into three subgroups based on intervals ( = 5).