Publications by authors named "H Sundh"
The Atlantic wolffish (Anarhichas lupus) is a cold-water fish with potential for aquaculture diversification. To unveil the mechanisms underlying the compromised growth in Atlantic wolffish when reared at higher temperatures, we investigated the relationship between temperature, growth rate, aerobic capacity, stress biomarkers, and gut barrier function. Juveniles acclimated to 10°C were maintained at 10°C (control) or exposed to 15°C for either 24 h (acute exposure) or 50 days (chronic exposure).
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- Most fish gastrointestinal research has been conducted in unrealistic lab conditions that don't accurately reflect the complex environments found in live fish, including variations in ionic conditions, pH, and oxygen levels.
- The gut microbiome, crucial for normal gut function, is hard to replicate in lab settings, complicating research further.
- To improve research accuracy, it's important to consider gut compartment chemistry, maintain microbiome diversity, and develop solutions that mimic live conditions, potentially by using advanced technologies like 'gut-on-chip' devices from mammalian studies.
Infections pose a challenge for the fast growing aquaculture sector. Glycosphingolipids are cell membrane components that pathogens utilize for attachment to the host to initiate infection. Here, we characterized rainbow trout glycosphingolipids from five mucosal tissues using mass spectrometry and nuclear magnetic resonance and investigated binding of radiolabeled Aeromonas salmonicida to the glycosphingolipids on thin-layer chromatograms.
View Article and Find Full Text PDFMucosal tissues appear to be more important in fish than in mammals due to living in a microbial-rich aquatic milieu, yet the complex interaction between the immune and the neuroendocrine system in these tissues remains elusive. The aim of this work was to investigate the mucosal immune response in immunized rainbow trout vaccinated with Alpha ject vaccine (bivalent), kept in fresh water (FW) or transferred to seawater (SW), and to evaluate their response to acute stress (chasing). Acute stress resulted in higher levels of plasma cortisol (Sham + Stress and Vaccine + Stress).
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- The study aimed to determine the optimal dietary protein requirement for juvenile Atlantic wolffish in aquaculture, testing diets with crude protein levels from 35% to 60%.
- The highest protein diet (60%) led to the best growth rates, with significant weight gain and specific growth rates observed, while the lower protein diets provided lesser growth.
- Despite increased hepatic lipid deposition in fish consuming high-protein diets, overall welfare indicators like plasma cortisol and glucose levels showed no diet-related effects, suggesting that a minimum protein level of 50% is essential for growth.