Publications by authors named "H Sumi"
Article Synopsis
- - Intercalation reactions depend on how the electronic and structural properties of host (like TaS) and guest materials (like divalent ions) interact, making it harder for divalent ions like Mg to intercalate compared to monovalent ions.
- - This study explores the cointercalation of Mg and hydrogen (H) into TaS to produce bulk polycrystalline MgHTaS, where hydrogen can be removed by heating at around 400 °C without changing the crystal structure.
- - The research also investigates how the superconducting properties relate to electronic carrier density using both theoretical calculations and experiments, highlighting the benefits of using hydrides for intercalation reactions.
Background: Mouse double minute-2 homolog (MDM2) plays a key role in downregulating p53 activity in hematologic malignancies, and its overexpression is associated with poor outcomes.
Methods: This phase 1 study assessed the safety and efficacy of different dosing regimens of the MDM2 inhibitor milademetan as monotherapy and in combination with azacitidine (AZA) in patients with relapsed or refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.
Results: Seventy-four patients (monotherapy, n = 57; milademetan-AZA combination, n = 17) were treated.
Aims: Wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) is often accompanied by atrial fibrillation (AF), atrial flutter (AFL), and atrial tachycardia (AT), which are difficult to control because beta-blockers and antiarrhythmic drugs can worsen heart failure (HF). This study aimed to investigate the outcomes of catheter ablation (CA) for AF/AFL/AT in patients with ATTRwt-CM and propose a treatment strategy for CA.
Methods And Results: A cohort study was conducted on 233 patients diagnosed with ATTRwt-CM, including 54 who underwent CA for AF/AFL/AT.