Publications by authors named "H Stephen Injeyan"
Objective: The objective of this study was to determine whether seated cervical manipulation produced changes in autonomic nervous system activity, as measured by heart rate variability and plasma norepinephrine levels.
Methods: Ninety-five healthy young adults (ages 20-48 years) were recruited into a single-blinded physiological study, with 47 randomized to a seated cervical manipulation and 44 randomized to a sham procedure. Heart rate variability in the frequency domain, and plasma norepinephrine levels were measured prior to, immediately following, and 5 minutes following the intervention.
Article Synopsis
- Force-Based Manipulation (FBM), which includes techniques like light touch and thrust manipulation, is widely used to alleviate pain, but the specific mechanisms behind its effectiveness are not well understood.
- A study identified 37 research gaps related to FBM by employing an international nominal group technique, with 23 gaps achieving consensus, particularly highlighting the strong influence of contextual factors and the need for studies on different pain phenotypes.
- The findings suggest that understanding individual differences in pain response could enhance precision medicine approaches in pain management, emphasizing the importance of mechanism-based research in clinical settings.
Article Synopsis
- The study investigates the role of the inflammatory biomarker HMGB1 in chronic low back pain (LBP) by comparing patients with LBP to asymptomatic individuals.
- It finds significantly higher extracellular HMGB1 levels and altered gene expression of TNFα and IL-1β in LBP patients, correlating with pain intensity scores.
- The research suggests that HMGB1 could be a key factor in the inflammatory processes associated with chronic non-specific LBP.
Objective: The purpose of this study was to identify sources and strategies for the mitigation of bias in studies of spinal manipulation and heart rate variability.
Methods: A small-scale study compared the effects of a single session of sham and authentic cervical manipulation on heart rate variability as measured by power spectrum analysis. The participants were a sample of 31 healthy young students from the Canadian Memorial Chiropractic College, randomized into 2 study arms.
Background: There is a dearth of information about health education clinical file audits in the context of completeness of records and demonstrating program-wide competency achievement. We report on the reliability of an audit instrument used for electronic health record (EHR) audits in the clinics of a chiropractic college in Canada.
Methods: The instrument is a checklist built within an electronic software application designed to pull data automatically from the EHR.