[The pioneers Schwerin and Brandenburg-Görden in the development of alcohol use disorder therapy in the GDR].

Objective: The aim of this study was to provide insights into the addiction therapy concepts applied at the clinics of Hugo von Keyserlingk in Schwerin and Hubertus Windischmann in Brandenburg and to enable an understanding of the specific problems in this subsector of psychiatric care in the GDR.

Methods: Works published primarily in the GDR were identified, analyzed and contextualized, with expert interviews with von Keyserlingk and Windischmann complementing the findings.

Results: Initially limited approaches to alcoholism treatment after the Second World War gradually developed into more complex and diverse structures.

Field-Induced Antiferromagnetic Correlations in a Nanopatterned Van der Waals Ferromagnet: A Potential Artificial Spin Ice.

Nano-patterned magnetic materials have opened new venues for the investigation of strongly correlated phenomena including artificial spin-ice systems, geometric frustration, and magnetic monopoles, for technologically important applications such as reconfigurable ferromagnetism. With the advent of atomically thin 2D van der Waals (vdW) magnets, a pertinent question is whether such compounds could make their way into this realm where interactions can be tailored so that unconventional states of matter can be assessed. Here, it is shown that square islands of CrGeTe vdW ferromagnets distributed in a grid manifest antiferromagnetic correlations, essential to enable frustration resulting in an artificial spin-ice.

Assessment of the physiological effects and safety of transpulmonary chemoembolization with doxorubicin on pulmonary tissue using a human-isolated lung perfusion model.

Background: Whole lung transpulmonary chemoembolization using a combination of doxorubicin (DXO) and degradable starch microspheres (DSM-TPCE) might be a promising treatment option in soft tissue sarcoma. To pave the way for clinical studies, this study aimed to evaluate the short-term effects of DSM-TPCE with DXO using an ex vivo isolated lung perfusion (ILP) model.

Methods: Nine lung specimens retrieved from patients undergoing lobectomy underwent ex vivo ILP.

The transition-metal-dichalcogenide family as a superconductor tuned by charge density wave strength.

In metallic transition metal dichalcogenides (TMDs), which remain superconducting down to single-layer thickness, the critical temperature T decreases for Nb-based, and increases for Ta-based materials. This contradicting trend is puzzling, impeding the development of a unified theory. Here we study the thickness-evolution of superconducting tunneling spectra in TaSheterostructures.