Publications by authors named "H Stabile"
Article Synopsis
- * RNASET2 is associated with NET formation upon activation of neutrophils by various stimuli, and it is found in both mature neutrophils and macrophages in inflamed tissues.
- * Research indicates that RNASET2 levels in circulation correlate with the severity of autoimmune diseases like rheumatoid arthritis, suggesting it may be influential in the disease's development and progression.
Article Synopsis
- Haemophilus ducreyi, initially known for causing chancroid, has recently been linked to skin ulcers in children from certain regions, with its transmission mechanisms still largely unclear.
- Recent studies suggest that local flies may play a role in transmitting H. ducreyi, particularly in South Pacific and West African areas, with detection of the bacteria's DNA on these insects.
- A study using common house flies demonstrated that a significant percentage (86.11%) could transmit viable H. ducreyi, establishing flies as potential vectors, thereby highlighting the need to further investigate insect involvement in such diseases.
Article Synopsis
- Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1) need the protein STAT4 to respond quickly to pathogens and help with immune defense.
- Research using genetic and transcriptomic methods revealed that STAT4 has different roles in the development of NK cells and ILC1, affecting their ability to fight infections.
- STAT4 helps control inflammation in the gut by modulating immune responses, especially by limiting the production of harmful molecules from certain T cells during intestinal inflammation.
Glioblastoma multiforme (GBM) has high mortality and recurrence rates. Malignancy resilience is ascribed to Glioblastoma Stem Cells (GSCs), which are resistant to Temozolomide (TMZ), the gold standard for GBM post-surgical treatment. However, Nitric Oxide (NO) has demonstrated anti-cancer efficacy in GBM cells, but its potential impact on GSCs remains unexplored.
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