Publications by authors named "H Srinivasan"
Over a century ago, Einstein formulated a precise mathematical model for describing Brownian motion. While this model adequately explains the diffusion of micron-sized particles in fluids, its limitations become apparent when applied to molecular self-diffusion in fluids. The foundational principles of Gaussianity and Markovianity, central to the Brownian diffusion paradigm, are insufficient for describing molecular diffusion, particularly in complex fluids characterized by intricate intermolecular interactions and hindered relaxation processes.
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- Ionic liquids (ILs) show potential in pharmaceuticals and green chemistry, but their use is limited due to toxicity concerns from interactions with cell membranes.
- This study investigates imidazolium-based ILs' effects on a model cell membrane made of DPPC lipids, revealing that the shorter-chain IL, HMIM[Br], causes DPPC vesicle aggregation, while the longer-chain IL, DMIM[Br], creates IL-poor and IL-rich nanodomains instead.
- Findings indicate that the formation of membrane nanodomains correlates with increased membrane permeability and cytotoxicity of longer-chain ILs, providing insights for developing safer ILs for biomedical and industrial applications.
Article Synopsis
- - The study investigates how the gut microbiome is related to colorectal cancer (CRC) and health, finding that about 23-40% of gut bacteria are associated with either CRC or overall health.
- - Researchers utilized advanced sequencing techniques to identify and analyze protein-coding gene clusters, discovering 2,319 co-abundant gene clusters related to CRC, including many previously unknown bacteria linked to the disease.
- - The findings provide evidence that certain gut bacteria can influence precancerous conditions in the colon and suggest that understanding these microbial connections could lead to new cancer prevention strategies.
The lateral diffusion of lipids within a membrane is of paramount importance, serving as a central mechanism in numerous physiological processes including cell signaling, membrane trafficking, protein activity regulation, and energy transduction pathways. This review offers a comprehensive overview of lateral lipid diffusion in model biomembrane systems explored through the lens of neutron scattering techniques. We examine diverse models of lateral diffusion and explore the various factors influencing this fundamental process in membrane dynamics.
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- A woman in her 50s with breast cancer had some strange red growths on her neck and chest, but didn’t feel any pain from them.
- Doctors looked at the growths and thought they could be several different things, but after testing, they found out these growths were a rare type called eccrine poroma (EP).
- The woman had the growths removed using a special heat method, and a year later there was no sign of them coming back, showing how important it is to recognize EP when looking at similar-looking skin issues.