Publications by authors named "H Skarzynski"
Background/objectives: The aim of the study was to evaluate the prevalence of undiagnosed hearing impairment or central auditory processing disorders in children from I and VIII grades of primary schools in Warsaw.
Methods: The participants in the study were 15,659 pupils from classes I and VIII attending primary schools in Warsaw. As part of the study, the hearing threshold for air conduction at frequencies of 0.
Introduction: The electrically evoked stapedius reflex threshold (eSRT) is an objective measure that helps to fit cochlear implants (CIs). The primary aim of this study was to investigate the relationship between different burst durations to elicit eSRT in pediatric CI users.
Materials And Methods: Different stimuli burst durations (100-500 ms) were applied to observe the effect in the reflex determination in 11 pediatric CI users.
Purpose: This study aimed to investigate the relationships between generic health-related quality of life (HRQoL), the Big Five personality traits, speech understanding, and sociodemographic factors in a group of postlingually deaf cochlear implant (CI) users.
Method: The study group included 81 participants who met the inclusion criteria: profound sensorineural hearing loss, 18 years of age or more, and using at least one CI implanted after 18 years of age. Some 18% were bilateral CI users.
The aim of this study was to assess auditory development in young children with profound hearing loss, cochlear implants (CIs), and congenital cytomegalovirus (cCMV) infection and to determine the effect of comorbidities on their development. The study group (cCMV group) consisted of 47 CI children-18 girls and 29 boys-who had been diagnosed as having prelingual hearing loss due to cCMV infection (with or without comorbidities); the mean age at CI activation was 15.2 months (range: 9.
View Article and Find Full Text PDFZebrafish in-vivo study reveals deleterious activity of human TBC1D24 genetic variants linked with autosomal dominant hearing loss.
Biochim Biophys Acta Mol Basis Dis
February 2025
Article Synopsis
- Genetic variants in the TBC1D24 gene are linked to non-syndromic autosomal dominant hearing loss (ADHL), but their molecular mechanisms remain unclear.
- Researchers used zebrafish to study TBC1D24's role in hearing and how specific harmful mutations affect its function.
- Experiment results showed that knocking down TBC1D24 led to ear structure defects and movement issues in zebrafish embryos, with harmful mutations interfering more than normal gene expression, thus pinpointing TBC1D24's critical role in inner ear development and ciliary function.